Polymorphisms of SLCO1B1 Gene in Sundanese Ethnic Population of Tuberculosis Patients in Indonesia

Polymorphisms of SLCO1B1 Gene in Sundanese Ethnic Population of Tuberculosis Patients in Indonesia

Background: The blood level of rifampicin, one of the tuberculosis (TB) drugs, depends on the organic anion transporting polypeptide 1B1 (OATP1B1) in hepatocytes. This protein is encoded by the solute carrier organic anion 1B1 (SLCO1B1) gene. Its genetic variation has been reported to have an impact...

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Bibliographic Details
Main Authors: Prayudi Santoso, Henny Juliastuti, Heda Melinda Nataprawira, Arto Yuwono Soeroto, Bachti Alisjahbana, Rovina Ruslami, Josephine Debora, Yunia Sribudiani, Ani Melani Maskoen
Format: Article
Language:English
Published: Interna Publishing 2023-01-01
Series:Acta Medica Indonesiana
Subjects:
c.85-7793C>T (rs4149032)
c.463C>A (rs11045819)
drug transporter
gene polymorphism
West Java
Indonesia
Online Access:http://www.actamedindones.org/index.php/ijim/article/view/2114
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