Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenance
Objective: To determine whether pharmacist is able to guaranteecold chain maintenance of thermolabile drugs during transportusing the available information in the reception processand to compare these results with those obtained in a subsequentintervention phase, in which the manufacturing laborator...
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| Format: | Article |
| Language: | English |
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Elsevier
2014-05-01
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| Series: | Farmacia Hospitalaria |
| Subjects: | |
| Online Access: | http://www.aulamedica.es/fh/pdf/1123.pdf |
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| author | I. Ricote-Lobera B. Santos-Mena S. Fraile-Gil B. Ortiz-Martín F. J. Hidalgo-Correas B. García-Díaz |
| author_facet | I. Ricote-Lobera B. Santos-Mena S. Fraile-Gil B. Ortiz-Martín F. J. Hidalgo-Correas B. García-Díaz |
| author_sort | I. Ricote-Lobera |
| collection | DOAJ |
| description | Objective: To determine whether pharmacist is able to guaranteecold chain maintenance of thermolabile drugs during transportusing the available information in the reception processand to compare these results with those obtained in a subsequentintervention phase, in which the manufacturing laboratorieswere contacted.
Methods: Intervention study, prospective and comparative“before-after”. It was analyzed the storage conditions duringtransport of all thermolabile drugs received in a 400-bed hospitalfor 3 months, excluding those from clinical trials.
Results: The intervention allowed to ensure cold chain maintenancein 76,5% (n = 488) of received drugs, representing anincrease of 41,8% (IC 95% 36,7-46,6%; p < 0,001) comparedwith the percentage obtained before the intervention.
Conclusions: The pharmacist isn’t able to ensure the cold chainmaintenance of received thermolabile drugs without temperaturemonitoring device (64,6%). Reports requested from laboratoriesallowed to increase significantly that percentage. |
| format | Article |
| id | doaj-art-df4c8823e40e4d1e8072cbb13f4458c9 |
| institution | OA Journals |
| issn | 1130-6343 2171-8695 |
| language | English |
| publishDate | 2014-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Farmacia Hospitalaria |
| spelling | doaj-art-df4c8823e40e4d1e8072cbb13f4458c92025-08-20T02:18:04ZengElsevierFarmacia Hospitalaria1130-63432171-86952014-05-0138321121510.7399/fh.2014.38.3.1123Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenanceI. Ricote-Lobera0B. Santos-Mena1S. Fraile-Gil2B. Ortiz-Martín3F. J. Hidalgo-Correas4B. García-Díaz5Residente de Farmacia Hospitalaria. Servicio de Farmacia. Hospital Universitario Severo Ochoa. Leganés. Madrid. España.Residente de Farmacia Hospitalaria. Servicio de Farmacia. Hospital Universitario Severo Ochoa. Leganés. Madrid. España.FEA Farmacia. Servicio de Farmacia. Hospital Universitario Severo Ochoa. Leganés. Madrid. España.Residente de Farmacia Hospitalaria. Servicio de Farmacia. Hospital Universitario Severo Ochoa. Leganés. Madrid. España.FEA Farmacia. Servicio de Farmacia. Hospital Universitario Severo Ochoa. Leganés. Madrid. EspañaJefe de Servicio. Servicio de Farmacia. Hospital Universitario Severo Ochoa. Leganés. Madrid. España.Objective: To determine whether pharmacist is able to guaranteecold chain maintenance of thermolabile drugs during transportusing the available information in the reception processand to compare these results with those obtained in a subsequentintervention phase, in which the manufacturing laboratorieswere contacted. Methods: Intervention study, prospective and comparative“before-after”. It was analyzed the storage conditions duringtransport of all thermolabile drugs received in a 400-bed hospitalfor 3 months, excluding those from clinical trials. Results: The intervention allowed to ensure cold chain maintenancein 76,5% (n = 488) of received drugs, representing anincrease of 41,8% (IC 95% 36,7-46,6%; p < 0,001) comparedwith the percentage obtained before the intervention. Conclusions: The pharmacist isn’t able to ensure the cold chainmaintenance of received thermolabile drugs without temperaturemonitoring device (64,6%). Reports requested from laboratoriesallowed to increase significantly that percentage.http://www.aulamedica.es/fh/pdf/1123.pdfCold chainThermolabile drugs;Drug stabilityDrug distributionRefrigerationPharmacist interventionProtocol; Quality |
| spellingShingle | I. Ricote-Lobera B. Santos-Mena S. Fraile-Gil B. Ortiz-Martín F. J. Hidalgo-Correas B. García-Díaz Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenance Farmacia Hospitalaria Cold chain Thermolabile drugs; Drug stability Drug distribution Refrigeration Pharmacist intervention Protocol ; Quality |
| title | Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenance |
| title_full | Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenance |
| title_fullStr | Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenance |
| title_full_unstemmed | Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenance |
| title_short | Thermolabile drugs: pharmacist intevention as a guarantee of cold chain maintenance |
| title_sort | thermolabile drugs pharmacist intevention as a guarantee of cold chain maintenance |
| topic | Cold chain Thermolabile drugs; Drug stability Drug distribution Refrigeration Pharmacist intervention Protocol ; Quality |
| url | http://www.aulamedica.es/fh/pdf/1123.pdf |
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