A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study
Abstract Background and objectives: Sickle cell disease (SCD) is hallmarked by recurrent episodes of severe acute pain and the risk for chronic pain. Remote peer support programs have been shown to effectively improve health outcomes for many chronic conditions. The objective of this study was to...
Saved in:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2025-01-01
|
| Series: | Journal of Clinical and Translational Science |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2059866124011701/type/journal_article |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832591631317991424 |
|---|---|
| author | Lauren Kelenc Brittany Wiles Fareha Nishat Chitra Lalloo Anya Nair Craig Eling Melanie Kirby-Allen Ewurabena Simpson Roona Sinha Richard Ward William T. Zempsky Sara Ahola Kohut Jennifer N. Stinson |
| author_facet | Lauren Kelenc Brittany Wiles Fareha Nishat Chitra Lalloo Anya Nair Craig Eling Melanie Kirby-Allen Ewurabena Simpson Roona Sinha Richard Ward William T. Zempsky Sara Ahola Kohut Jennifer N. Stinson |
| author_sort | Lauren Kelenc |
| collection | DOAJ |
| description |
Abstract
Background and objectives:
Sickle cell disease (SCD) is hallmarked by recurrent episodes of severe acute pain and the risk for chronic pain. Remote peer support programs have been shown to effectively improve health outcomes for many chronic conditions. The objective of this study was to examine the feasibility and acceptability of an online peer mentoring program (iPeer2Peer program) for adolescents with SCD.
Method:
A waitlist pilot randomized controlled trial was conducted. Adolescents randomized to the intervention group were matched with trained peer mentors (19–25 years; successfully managing their SCD), consisting of up to 10 sessions of approximately 30-min video calls over a 15-week period. The control group received standard care. The primary outcomes were rates of accrual, withdrawal, and adherence to iP2P program/protocol, with secondary outcomes identifying topics of mentorship–mentee conversations through qualitative analysis.
Results:
Twenty-eight participants (14 intervention; 14 control) were randomized to the study (mean age: 14.8 ± 1.7 years; 57% female). Accrual rate was 80% (28/35) and withdrawal rate was 18% (5/28), with 28% (4/14) adhering to the iP2P program; however, 71% (10/14) of adolescents in the intervention completed at least one call. Based on content analysis of 75 mentor–mentee calls, three distinct content categories emerged: impact of SCD, self-management, transitioning to adulthood with SCD, and general topics.
Conclusion:
The results from this pilot study suggest that the current iteration of the iP2P SCD program lacks feasibility. Future research with the iP2P program can focus improved engagement via personalized mentoring, variable communication avenues, and an emphasis on gender.
|
| format | Article |
| id | doaj-art-df3e4c25b8c7419d9b7fafe48e490368 |
| institution | Kabale University |
| issn | 2059-8661 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj-art-df3e4c25b8c7419d9b7fafe48e4903682025-01-22T08:24:17ZengCambridge University PressJournal of Clinical and Translational Science2059-86612025-01-01910.1017/cts.2024.1170A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method studyLauren Kelenc0Brittany Wiles1Fareha Nishat2Chitra Lalloo3Anya Nair4Craig Eling5Melanie Kirby-Allen6Ewurabena Simpson7Roona Sinha8Richard Ward9William T. Zempsky10Sara Ahola Kohut11Jennifer N. Stinson12https://orcid.org/0000-0002-9969-8052Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, CanadaChild Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, CanadaChild Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, CanadaChild Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, CanadaChild Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, CanadaJim Pattison’s Children’s Hospital, Saskatoon, Saskatchewan, CanadaDivision of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, CanadaDivision of Haematology/Oncology, Children’s Hospital of Eastern Ontario, Ottawa, Ontario, CanadaJim Pattison’s Children’s Hospital, Saskatoon, Saskatchewan, CanadaToronto General Hospital, University Health Network, Toronto, Ontario, Canada Department of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, CanadaDivision of Pain & Palliative Medicine, Connecticut Children’s Medical Center, Hartford, CT, USA Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USAChild Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada Division of Gastroenterology Hepatology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, CanadaChild Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada Lawrence S Bloomberg Faculty of Nursing, University of Toronto, Toronto, Canada Abstract Background and objectives: Sickle cell disease (SCD) is hallmarked by recurrent episodes of severe acute pain and the risk for chronic pain. Remote peer support programs have been shown to effectively improve health outcomes for many chronic conditions. The objective of this study was to examine the feasibility and acceptability of an online peer mentoring program (iPeer2Peer program) for adolescents with SCD. Method: A waitlist pilot randomized controlled trial was conducted. Adolescents randomized to the intervention group were matched with trained peer mentors (19–25 years; successfully managing their SCD), consisting of up to 10 sessions of approximately 30-min video calls over a 15-week period. The control group received standard care. The primary outcomes were rates of accrual, withdrawal, and adherence to iP2P program/protocol, with secondary outcomes identifying topics of mentorship–mentee conversations through qualitative analysis. Results: Twenty-eight participants (14 intervention; 14 control) were randomized to the study (mean age: 14.8 ± 1.7 years; 57% female). Accrual rate was 80% (28/35) and withdrawal rate was 18% (5/28), with 28% (4/14) adhering to the iP2P program; however, 71% (10/14) of adolescents in the intervention completed at least one call. Based on content analysis of 75 mentor–mentee calls, three distinct content categories emerged: impact of SCD, self-management, transitioning to adulthood with SCD, and general topics. Conclusion: The results from this pilot study suggest that the current iteration of the iP2P SCD program lacks feasibility. Future research with the iP2P program can focus improved engagement via personalized mentoring, variable communication avenues, and an emphasis on gender. https://www.cambridge.org/core/product/identifier/S2059866124011701/type/journal_articleOnlinepeer supportfeasibilityadolescentsickle cell diseaseself-management |
| spellingShingle | Lauren Kelenc Brittany Wiles Fareha Nishat Chitra Lalloo Anya Nair Craig Eling Melanie Kirby-Allen Ewurabena Simpson Roona Sinha Richard Ward William T. Zempsky Sara Ahola Kohut Jennifer N. Stinson A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study Journal of Clinical and Translational Science Online peer support feasibility adolescent sickle cell disease self-management |
| title | A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study |
| title_full | A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study |
| title_fullStr | A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study |
| title_full_unstemmed | A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study |
| title_short | A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study |
| title_sort | pilot randomized controlled trial of the ipeer2peer program in adolescents with sickle cell disease a mixed method study |
| topic | Online peer support feasibility adolescent sickle cell disease self-management |
| url | https://www.cambridge.org/core/product/identifier/S2059866124011701/type/journal_article |
| work_keys_str_mv | AT laurenkelenc apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT brittanywiles apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT farehanishat apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT chitralalloo apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT anyanair apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT craigeling apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT melaniekirbyallen apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT ewurabenasimpson apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT roonasinha apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT richardward apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT williamtzempsky apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT saraaholakohut apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT jennifernstinson apilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT laurenkelenc pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT brittanywiles pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT farehanishat pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT chitralalloo pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT anyanair pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT craigeling pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT melaniekirbyallen pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT ewurabenasimpson pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT roonasinha pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT richardward pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT williamtzempsky pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT saraaholakohut pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy AT jennifernstinson pilotrandomizedcontrolledtrialoftheipeer2peerprograminadolescentswithsicklecelldiseaseamixedmethodstudy |