Augmentation Therapy With Serotonin 5‐HT1A Receptor Partial Agonists on Cognitive Function in Depressive Disorders: A Systematic Review of Randomized Controlled Studies

Augmentation Therapy With Serotonin 5‐HT1A Receptor Partial Agonists on Cognitive Function in Depressive Disorders: A Systematic Review of Randomized Controlled Studies

ABSTRACT Objective The use of serotonin 5‐HT1A receptor partial agonists (5‐HT1A‐PAs) as an add‐on therapy has been associated with the enhancement of attention/processing speed in patients with schizophrenia. Also, 5‐HT1A receptors have been shown to play a role in the pathophysiology of mood disor...

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Bibliographic Details
Main Authors: Risa Yamada, Ayumu Wada, Andrew Stickley, Adrian Newman‐Tancredi, Tomiki Sumiyoshi
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Neuropsychopharmacology Reports
Subjects:
5‐HT1A receptor biased agonists
5‐HT1A receptor partial agonists
azapirone derivative
cognitive impairment
depression
Online Access:https://doi.org/10.1002/npr2.70023
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