Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement

Objective: To determine the efficacy of tranexamic acid in reducing blood loss in primary total knee replacement. Material and Methods: A total of 96 patients having a diagnosis of primary knee osteoarthritis made up the population sample. The Total Knee Replacement patients were separated into...

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Main Authors: Muhammad Inaamullah Younas, Faizan Rauf, Muhammad Sheraz Mustafa, Sarmad Nasir Janjua, Shaheen Iqbal, Khurram Habib
Format: Article
Language:English
Published: Rawalpindi Medical University 2023-06-01
Series:Journal of Rawalpindi Medical College
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Online Access:https://www.journalrmc.com/index.php/JRMC/article/view/2064
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author Muhammad Inaamullah Younas
Faizan Rauf
Muhammad Sheraz Mustafa
Sarmad Nasir Janjua
Shaheen Iqbal
Khurram Habib
author_facet Muhammad Inaamullah Younas
Faizan Rauf
Muhammad Sheraz Mustafa
Sarmad Nasir Janjua
Shaheen Iqbal
Khurram Habib
author_sort Muhammad Inaamullah Younas
collection DOAJ
description Objective: To determine the efficacy of tranexamic acid in reducing blood loss in primary total knee replacement. Material and Methods: A total of 96 patients having a diagnosis of primary knee osteoarthritis made up the population sample. The Total Knee Replacement patients were separated into two groups. Patients in Group B used Intra venous tranexamic acid, but those in Group A did not use tranexamic acid during the course of the operation or afterwards. Results: Mean age of the patients recorded in group A 63.79±6.60 (years) and in group B 62.96±7.89 (years). The majority of the patients in both groups were females. After surgery, Group B patients who received tranexamic acid reported less blood loss and less haemoglobin reduction as compared to the control group. Conclusion: From our study, we conclude that Tranexamic acid used intravenously during total knee arthroplasty considerably lowers postoperative blood loss.
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institution Kabale University
issn 1683-3562
1683-3570
language English
publishDate 2023-06-01
publisher Rawalpindi Medical University
record_format Article
series Journal of Rawalpindi Medical College
spelling doaj-art-df28bb03f1224c8f99e96c6482f0a9ac2025-02-06T08:41:51ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702023-06-0127210.37939/jrmc.v27i2.2064Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee ReplacementMuhammad Inaamullah YounasFaizan RaufMuhammad Sheraz MustafaSarmad Nasir JanjuaShaheen IqbalKhurram Habib Objective: To determine the efficacy of tranexamic acid in reducing blood loss in primary total knee replacement. Material and Methods: A total of 96 patients having a diagnosis of primary knee osteoarthritis made up the population sample. The Total Knee Replacement patients were separated into two groups. Patients in Group B used Intra venous tranexamic acid, but those in Group A did not use tranexamic acid during the course of the operation or afterwards. Results: Mean age of the patients recorded in group A 63.79±6.60 (years) and in group B 62.96±7.89 (years). The majority of the patients in both groups were females. After surgery, Group B patients who received tranexamic acid reported less blood loss and less haemoglobin reduction as compared to the control group. Conclusion: From our study, we conclude that Tranexamic acid used intravenously during total knee arthroplasty considerably lowers postoperative blood loss. https://www.journalrmc.com/index.php/JRMC/article/view/2064Total knee replacement, Tranexamic acid, Efficacy.
spellingShingle Muhammad Inaamullah Younas
Faizan Rauf
Muhammad Sheraz Mustafa
Sarmad Nasir Janjua
Shaheen Iqbal
Khurram Habib
Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement
Journal of Rawalpindi Medical College
Total knee replacement, Tranexamic acid, Efficacy.
title Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement
title_full Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement
title_fullStr Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement
title_full_unstemmed Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement
title_short Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement
title_sort efficacy of tranexamic acid in reducing blood loss in primary total knee replacement
topic Total knee replacement, Tranexamic acid, Efficacy.
url https://www.journalrmc.com/index.php/JRMC/article/view/2064
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AT sarmadnasirjanjua efficacyoftranexamicacidinreducingbloodlossinprimarytotalkneereplacement
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