Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement

Objective: To determine the efficacy of tranexamic acid in reducing blood loss in primary total knee replacement. Material and Methods: A total of 96 patients having a diagnosis of primary knee osteoarthritis made up the population sample. The Total Knee Replacement patients were separated into...

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Bibliographic Details
Main Authors: Muhammad Inaamullah Younas, Faizan Rauf, Muhammad Sheraz Mustafa, Sarmad Nasir Janjua, Shaheen Iqbal, Khurram Habib
Format: Article
Language:English
Published: Rawalpindi Medical University 2023-06-01
Series:Journal of Rawalpindi Medical College
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Online Access:https://www.journalrmc.com/index.php/JRMC/article/view/2064
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Summary:Objective: To determine the efficacy of tranexamic acid in reducing blood loss in primary total knee replacement. Material and Methods: A total of 96 patients having a diagnosis of primary knee osteoarthritis made up the population sample. The Total Knee Replacement patients were separated into two groups. Patients in Group B used Intra venous tranexamic acid, but those in Group A did not use tranexamic acid during the course of the operation or afterwards. Results: Mean age of the patients recorded in group A 63.79±6.60 (years) and in group B 62.96±7.89 (years). The majority of the patients in both groups were females. After surgery, Group B patients who received tranexamic acid reported less blood loss and less haemoglobin reduction as compared to the control group. Conclusion: From our study, we conclude that Tranexamic acid used intravenously during total knee arthroplasty considerably lowers postoperative blood loss.
ISSN:1683-3562
1683-3570