MHC2-SCALE enhances identification of immunogenic neoantigens
Summary: Recent studies suggest that CD4+ T cells can exert potent anti-tumor effects and improve immunotherapy efficacy by aiding CD8+ T cells. However, characterizing the mechanism of CD4+ T cells’ anti-tumor activity has been challenging due to inaccurate major histocompatibility complex class II...
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| Main Authors: | Joshua G. Gober, Aude-Hélène Capietto, Reyhane Hoshyar, Martine Darwish, Richard Vandlen, Jonathan L. Linehan, Lélia Delamarre, Adel M. ElSohly |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-04-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225004730 |
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