61 Phase 2 Clinical trial success: Association with statistical decision-making in preceding rodent experiments
Objectives/Goals: In neurological animal research, statistical misapplication may lead to overoptimism in a therapy’s potential for successful translation. This pilot study investigated whether human clinical trials that fail have higher prevalence of statistical misapplication in preceding animal e...
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| Main Authors: | Olivia Hogue, Megan Zelinsky, Claire Sonneborn, Mary A Dolanksy, Nancy A Obuchowski, Kenneth B Baker, Jill S. Barnholtz-Sloan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2025-04-01
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| Series: | Journal of Clinical and Translational Science |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2059866124007404/type/journal_article |
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