Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic Leukemia

We report a case of a child survival after extracorporeal membrane oxygenation (ECMO) support of 25 days for cardiopulmonary failure and septic shock in the context of juvenile myelomonocytic leukemia (JMML). ECMO support is still a matter of debate for the management of septic patients with maligna...

Full description

Saved in:
Bibliographic Details
Main Authors: Maris Bartkevics, Bert Hennig, Tayfun Gungor, Roland Ammann, Alexander Kadner
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2020/5696380
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832550454434725888
author Maris Bartkevics
Bert Hennig
Tayfun Gungor
Roland Ammann
Alexander Kadner
author_facet Maris Bartkevics
Bert Hennig
Tayfun Gungor
Roland Ammann
Alexander Kadner
author_sort Maris Bartkevics
collection DOAJ
description We report a case of a child survival after extracorporeal membrane oxygenation (ECMO) support of 25 days for cardiopulmonary failure and septic shock in the context of juvenile myelomonocytic leukemia (JMML). ECMO support is still a matter of debate for the management of septic patients with malignancy. However, these patients are at increased risk for early death secondary to pulmonary complications due to leukostasis, direct pulmonary infiltration with WBC, and systemic inflammatory response syndrome following malignant cell lysis. Despite the high risk of complications, ECMO support must be discussed as part of management, providing better outcome in this group of patients.
format Article
id doaj-art-deebf725951f41d4b676161ba68b0d5e
institution Kabale University
issn 2090-6560
2090-6579
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Case Reports in Hematology
spelling doaj-art-deebf725951f41d4b676161ba68b0d5e2025-02-03T06:06:43ZengWileyCase Reports in Hematology2090-65602090-65792020-01-01202010.1155/2020/56963805696380Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic LeukemiaMaris Bartkevics0Bert Hennig1Tayfun Gungor2Roland Ammann3Alexander Kadner4Center for Congenital Heart Disease, Department of Cardiovascular Surgery, Inselspital University Hospital, Bern University, Bern, SwitzerlandDepartment of Pediatrics, University Children’s Hospital, Bern University, Bern, SwitzerlandDepartment of Stem Cell Transplantation, University Children’s Hospital Zurich, University Zurich, Zürich, SwitzerlandDepartment of Pediatrics, University Children’s Hospital, Bern University, Bern, SwitzerlandCenter for Congenital Heart Disease, Department of Cardiovascular Surgery, Inselspital University Hospital, Bern University, Bern, SwitzerlandWe report a case of a child survival after extracorporeal membrane oxygenation (ECMO) support of 25 days for cardiopulmonary failure and septic shock in the context of juvenile myelomonocytic leukemia (JMML). ECMO support is still a matter of debate for the management of septic patients with malignancy. However, these patients are at increased risk for early death secondary to pulmonary complications due to leukostasis, direct pulmonary infiltration with WBC, and systemic inflammatory response syndrome following malignant cell lysis. Despite the high risk of complications, ECMO support must be discussed as part of management, providing better outcome in this group of patients.http://dx.doi.org/10.1155/2020/5696380
spellingShingle Maris Bartkevics
Bert Hennig
Tayfun Gungor
Roland Ammann
Alexander Kadner
Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic Leukemia
Case Reports in Hematology
title Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic Leukemia
title_full Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic Leukemia
title_fullStr Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic Leukemia
title_full_unstemmed Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic Leukemia
title_short Prolonged Pediatric Extracorporeal Membrane Oxygenation Support with Cardiopulmonary Failure in Juvenile Myelomonocytic Leukemia
title_sort prolonged pediatric extracorporeal membrane oxygenation support with cardiopulmonary failure in juvenile myelomonocytic leukemia
url http://dx.doi.org/10.1155/2020/5696380
work_keys_str_mv AT marisbartkevics prolongedpediatricextracorporealmembraneoxygenationsupportwithcardiopulmonaryfailureinjuvenilemyelomonocyticleukemia
AT berthennig prolongedpediatricextracorporealmembraneoxygenationsupportwithcardiopulmonaryfailureinjuvenilemyelomonocyticleukemia
AT tayfungungor prolongedpediatricextracorporealmembraneoxygenationsupportwithcardiopulmonaryfailureinjuvenilemyelomonocyticleukemia
AT rolandammann prolongedpediatricextracorporealmembraneoxygenationsupportwithcardiopulmonaryfailureinjuvenilemyelomonocyticleukemia
AT alexanderkadner prolongedpediatricextracorporealmembraneoxygenationsupportwithcardiopulmonaryfailureinjuvenilemyelomonocyticleukemia