No evidence of pathogenic involvement of cathelicidins in patient cohorts and mouse models of lupus and arthritis.

No evidence of pathogenic involvement of cathelicidins in patient cohorts and mouse models of lupus and arthritis.

Apart from their role in the immune defence against pathogens evidence of a role of antimicrobial peptides (AMPs) in autoimmune diseases has accumulated in the past years. The aim of this project was to examine the functional impact of the human cathelicidin LL-37 and the mouse cathelicidin-related...

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Main Authors: D Kienhöfer, J Hahn, I Schubert, C Reinwald, N Ipseiz, S C Lang, È Bosch Borràs, K Amann, C Sjöwall, A E Barron, A J Hueber, B Agerberth, G Schett, M H Hoffmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0115474
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