Inhaled Nitric Oxide Counterbalances ET-1 Dependent Pulmonary Hypertension and Bronchoconstriction in the Pig

In anaesthetized, paralysed, ventilated pigs the ability of inhaled nitric oxide (80 ppm in 02) to reduce the haemodynamic and respiratory effects of endothelin-1 administration (200 pmol/kg, i.v.) was evaluated. The mechanical properties of the respiratory system were evaluated by the rapid airway...

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Bibliographic Details
Main Authors: M. G. Clement, M. Dimori
Format: Article
Language:English
Published: Wiley 1994-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935194000165
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