Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus Images

Age-related macular degeneration (AMD) is a disease which causes visual deficiency and irreversible blindness to the elderly. In this paper, an automatic classification method for AMD is proposed to perform robust and reproducible assessments in a telemedicine context. First, a study was carried out...

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Main Authors: Thanh Vân Phan, Lama Seoud, Hadi Chakor, Farida Cheriet
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2016/5893601
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author Thanh Vân Phan
Lama Seoud
Hadi Chakor
Farida Cheriet
author_facet Thanh Vân Phan
Lama Seoud
Hadi Chakor
Farida Cheriet
author_sort Thanh Vân Phan
collection DOAJ
description Age-related macular degeneration (AMD) is a disease which causes visual deficiency and irreversible blindness to the elderly. In this paper, an automatic classification method for AMD is proposed to perform robust and reproducible assessments in a telemedicine context. First, a study was carried out to highlight the most relevant features for AMD characterization based on texture, color, and visual context in fundus images. A support vector machine and a random forest were used to classify images according to the different AMD stages following the AREDS protocol and to evaluate the features’ relevance. Experiments were conducted on a database of 279 fundus images coming from a telemedicine platform. The results demonstrate that local binary patterns in multiresolution are the most relevant for AMD classification, regardless of the classifier used. Depending on the classification task, our method achieves promising performances with areas under the ROC curve between 0.739 and 0.874 for screening and between 0.469 and 0.685 for grading. Moreover, the proposed automatic AMD classification system is robust with respect to image quality.
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institution Kabale University
issn 2090-004X
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publishDate 2016-01-01
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spelling doaj-art-de9f33a951b542509548f81b8eb83b3d2025-02-03T01:09:25ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/58936015893601Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus ImagesThanh Vân Phan0Lama Seoud1Hadi Chakor2Farida Cheriet3Biomedical Engineering Institute of École Polytechnique de Montréal, Montréal, QC, H3C 3A7, CanadaDiagnos Inc., Brossard, QC, J4Z 1A7, CanadaDiagnos Inc., Brossard, QC, J4Z 1A7, CanadaDepartment of Computer and Software Engineering of École Polytechnique de Montréal, Montréal, QC, H3C 3A7, CanadaAge-related macular degeneration (AMD) is a disease which causes visual deficiency and irreversible blindness to the elderly. In this paper, an automatic classification method for AMD is proposed to perform robust and reproducible assessments in a telemedicine context. First, a study was carried out to highlight the most relevant features for AMD characterization based on texture, color, and visual context in fundus images. A support vector machine and a random forest were used to classify images according to the different AMD stages following the AREDS protocol and to evaluate the features’ relevance. Experiments were conducted on a database of 279 fundus images coming from a telemedicine platform. The results demonstrate that local binary patterns in multiresolution are the most relevant for AMD classification, regardless of the classifier used. Depending on the classification task, our method achieves promising performances with areas under the ROC curve between 0.739 and 0.874 for screening and between 0.469 and 0.685 for grading. Moreover, the proposed automatic AMD classification system is robust with respect to image quality.http://dx.doi.org/10.1155/2016/5893601
spellingShingle Thanh Vân Phan
Lama Seoud
Hadi Chakor
Farida Cheriet
Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus Images
Journal of Ophthalmology
title Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus Images
title_full Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus Images
title_fullStr Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus Images
title_full_unstemmed Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus Images
title_short Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus Images
title_sort automatic screening and grading of age related macular degeneration from texture analysis of fundus images
url http://dx.doi.org/10.1155/2016/5893601
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AT hadichakor automaticscreeningandgradingofagerelatedmaculardegenerationfromtextureanalysisoffundusimages
AT faridacheriet automaticscreeningandgradingofagerelatedmaculardegenerationfromtextureanalysisoffundusimages