Haemostatic Response of Polyethylene Terephthalate Treated by Oxygen and Nitrogen Plasma Afterglows
Samples of polymer polyethylene terephthalate were coated with heparin and the haemostatic response has been determined by optical imaging of samples after incubation with fresh blood from a healthy donor. Prior to coating the samples were treated by neutral reactive particles of the oxygen or nitro...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2016/1749285 |
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| author | Metod Kolar Gregor Primc |
| author_facet | Metod Kolar Gregor Primc |
| author_sort | Metod Kolar |
| collection | DOAJ |
| description | Samples of polymer polyethylene terephthalate were coated with heparin and the haemostatic response has been determined by optical imaging of samples after incubation with fresh blood from a healthy donor. Prior to coating the samples were treated by neutral reactive particles of the oxygen or nitrogen plasma flowing afterglow. X-ray photoelectron spectroscopy analysis showed intensive functionalization of the polymer foils upon treatment with afterglows; however, the concentration of sulphur from heparin remained below the detection limit. The optical imaging showed densely distributed blood platelets in highly activated forms on untreated samples, whereas treatment with both afterglows revealed improved hemocompatibility. Best results were obtained for oxygen-functionalized polymer, whereas additional coating with heparin caused moderate loss of hemocompatibility, that was explained by deactivation of surface functional groups upon incubation with heparin. |
| format | Article |
| id | doaj-art-de9bfeaf1858401baaa4e125ffa4611e |
| institution | Kabale University |
| issn | 1687-9422 1687-9430 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj-art-de9bfeaf1858401baaa4e125ffa4611e2025-02-03T01:23:30ZengWileyInternational Journal of Polymer Science1687-94221687-94302016-01-01201610.1155/2016/17492851749285Haemostatic Response of Polyethylene Terephthalate Treated by Oxygen and Nitrogen Plasma AfterglowsMetod Kolar0Gregor Primc1Centre of Excellence, PoliMat, Tehnološki Park 24, 1000 Ljubljana, SloveniaPlasmadis d.o.o., Teslova 30, 1000 Ljubljana, SloveniaSamples of polymer polyethylene terephthalate were coated with heparin and the haemostatic response has been determined by optical imaging of samples after incubation with fresh blood from a healthy donor. Prior to coating the samples were treated by neutral reactive particles of the oxygen or nitrogen plasma flowing afterglow. X-ray photoelectron spectroscopy analysis showed intensive functionalization of the polymer foils upon treatment with afterglows; however, the concentration of sulphur from heparin remained below the detection limit. The optical imaging showed densely distributed blood platelets in highly activated forms on untreated samples, whereas treatment with both afterglows revealed improved hemocompatibility. Best results were obtained for oxygen-functionalized polymer, whereas additional coating with heparin caused moderate loss of hemocompatibility, that was explained by deactivation of surface functional groups upon incubation with heparin.http://dx.doi.org/10.1155/2016/1749285 |
| spellingShingle | Metod Kolar Gregor Primc Haemostatic Response of Polyethylene Terephthalate Treated by Oxygen and Nitrogen Plasma Afterglows International Journal of Polymer Science |
| title | Haemostatic Response of Polyethylene Terephthalate Treated by Oxygen and Nitrogen Plasma Afterglows |
| title_full | Haemostatic Response of Polyethylene Terephthalate Treated by Oxygen and Nitrogen Plasma Afterglows |
| title_fullStr | Haemostatic Response of Polyethylene Terephthalate Treated by Oxygen and Nitrogen Plasma Afterglows |
| title_full_unstemmed | Haemostatic Response of Polyethylene Terephthalate Treated by Oxygen and Nitrogen Plasma Afterglows |
| title_short | Haemostatic Response of Polyethylene Terephthalate Treated by Oxygen and Nitrogen Plasma Afterglows |
| title_sort | haemostatic response of polyethylene terephthalate treated by oxygen and nitrogen plasma afterglows |
| url | http://dx.doi.org/10.1155/2016/1749285 |
| work_keys_str_mv | AT metodkolar haemostaticresponseofpolyethyleneterephthalatetreatedbyoxygenandnitrogenplasmaafterglows AT gregorprimc haemostaticresponseofpolyethyleneterephthalatetreatedbyoxygenandnitrogenplasmaafterglows |