SYNTHETIC STUDIES IN THE 6H-[1,2,4] TRIAZINO [3,4-b] [ 1,3,4] THIADIAZINES

4-Amino-6-methyl- 1,2,4-triazine-3(2H)-thione-5-0ne (1) was condensed with propargyl bromidein the presence of sodium rnethoxide to afford 3-propargylmercapto- 4-arnino-6-rnethyl-1,2,4-triazin-5-one(2) . Transformation of the latter to 8-dihydro- 3-methyl-7-methylene-4-oxo-6H-[1,2,4]TRIAZINO [3,4-b]...

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Format: Article
Language:English
Published: University of Tehran 1996-06-01
Series:Journal of Sciences, Islamic Republic of Iran
Online Access:https://jsciences.ut.ac.ir/article_31096_d67e0db85f6924b501d6b1f5bd7a9a93.pdf
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collection DOAJ
description 4-Amino-6-methyl- 1,2,4-triazine-3(2H)-thione-5-0ne (1) was condensed with propargyl bromidein the presence of sodium rnethoxide to afford 3-propargylmercapto- 4-arnino-6-rnethyl-1,2,4-triazin-5-one(2) . Transformation of the latter to 8-dihydro- 3-methyl-7-methylene-4-oxo-6H-[1,2,4]TRIAZINO [3,4-b] [1,3,4] thiadiazine (3) was performed under the condition of palladium (II) salt. Ring closure of (1) withphenacyl bromide provides the 3-methyl-7-phenyl-4-0x0-6h [1,2,4]triazino[3,4-b] [1,3,4] THIADIAZINE.
format Article
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issn 1016-1104
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publishDate 1996-06-01
publisher University of Tehran
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series Journal of Sciences, Islamic Republic of Iran
spelling doaj-art-de9092b00a314e039d9151ff9203c8482025-08-20T03:08:48ZengUniversity of TehranJournal of Sciences, Islamic Republic of Iran1016-11042345-69141996-06-017231096SYNTHETIC STUDIES IN THE 6H-[1,2,4] TRIAZINO [3,4-b] [ 1,3,4] THIADIAZINES4-Amino-6-methyl- 1,2,4-triazine-3(2H)-thione-5-0ne (1) was condensed with propargyl bromidein the presence of sodium rnethoxide to afford 3-propargylmercapto- 4-arnino-6-rnethyl-1,2,4-triazin-5-one(2) . Transformation of the latter to 8-dihydro- 3-methyl-7-methylene-4-oxo-6H-[1,2,4]TRIAZINO [3,4-b] [1,3,4] thiadiazine (3) was performed under the condition of palladium (II) salt. Ring closure of (1) withphenacyl bromide provides the 3-methyl-7-phenyl-4-0x0-6h [1,2,4]triazino[3,4-b] [1,3,4] THIADIAZINE.https://jsciences.ut.ac.ir/article_31096_d67e0db85f6924b501d6b1f5bd7a9a93.pdf
spellingShingle SYNTHETIC STUDIES IN THE 6H-[1,2,4] TRIAZINO [3,4-b] [ 1,3,4] THIADIAZINES
Journal of Sciences, Islamic Republic of Iran
title SYNTHETIC STUDIES IN THE 6H-[1,2,4] TRIAZINO [3,4-b] [ 1,3,4] THIADIAZINES
title_full SYNTHETIC STUDIES IN THE 6H-[1,2,4] TRIAZINO [3,4-b] [ 1,3,4] THIADIAZINES
title_fullStr SYNTHETIC STUDIES IN THE 6H-[1,2,4] TRIAZINO [3,4-b] [ 1,3,4] THIADIAZINES
title_full_unstemmed SYNTHETIC STUDIES IN THE 6H-[1,2,4] TRIAZINO [3,4-b] [ 1,3,4] THIADIAZINES
title_short SYNTHETIC STUDIES IN THE 6H-[1,2,4] TRIAZINO [3,4-b] [ 1,3,4] THIADIAZINES
title_sort synthetic studies in the 6h 1 2 4 triazino 3 4 b 1 3 4 thiadiazines
url https://jsciences.ut.ac.ir/article_31096_d67e0db85f6924b501d6b1f5bd7a9a93.pdf