Incidental Discovery of Multiorgan Extramedullary Plasmacytomas in the Setting of Newly Diagnosed Multiple Myeloma and Delayed Hemolytic Transfusion Reaction
Extramedullary plasmacytomas (EMPs) are defined by the presence of clonal plasma cell proliferation outside of the bone marrow, portending an overall poor prognosis. This case highlights extramedullary plasmacytomas as an unusual presenting manifestation of multiple myeloma. Through incidental disco...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2017/4531858 |
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| _version_ | 1832545817981878272 |
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| author | Joselle Cook Steven Song Anthony Ventimiglia Carol Luhrs |
| author_facet | Joselle Cook Steven Song Anthony Ventimiglia Carol Luhrs |
| author_sort | Joselle Cook |
| collection | DOAJ |
| description | Extramedullary plasmacytomas (EMPs) are defined by the presence of clonal plasma cell proliferation outside of the bone marrow, portending an overall poor prognosis. This case highlights extramedullary plasmacytomas as an unusual presenting manifestation of multiple myeloma. Through incidental discovery during a delayed hemolytic transfusion reaction workup, EMPs were found in the liver, spleen, and possibly the lung. Though rare at presentation, this case emphasizes that the presence of EMPs should be considered at the outset as it not only impacts the treatment regimen for such patients but also considerably affects prognosis. |
| format | Article |
| id | doaj-art-de90168e52bc4e45b4bd507fc01aa06e |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-de90168e52bc4e45b4bd507fc01aa06e2025-02-03T07:24:39ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/45318584531858Incidental Discovery of Multiorgan Extramedullary Plasmacytomas in the Setting of Newly Diagnosed Multiple Myeloma and Delayed Hemolytic Transfusion ReactionJoselle Cook0Steven Song1Anthony Ventimiglia2Carol Luhrs3Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203, USADepartment of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203, USACollege of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203, USADivision of Hematology and Oncology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USAExtramedullary plasmacytomas (EMPs) are defined by the presence of clonal plasma cell proliferation outside of the bone marrow, portending an overall poor prognosis. This case highlights extramedullary plasmacytomas as an unusual presenting manifestation of multiple myeloma. Through incidental discovery during a delayed hemolytic transfusion reaction workup, EMPs were found in the liver, spleen, and possibly the lung. Though rare at presentation, this case emphasizes that the presence of EMPs should be considered at the outset as it not only impacts the treatment regimen for such patients but also considerably affects prognosis.http://dx.doi.org/10.1155/2017/4531858 |
| spellingShingle | Joselle Cook Steven Song Anthony Ventimiglia Carol Luhrs Incidental Discovery of Multiorgan Extramedullary Plasmacytomas in the Setting of Newly Diagnosed Multiple Myeloma and Delayed Hemolytic Transfusion Reaction Case Reports in Hematology |
| title | Incidental Discovery of Multiorgan Extramedullary Plasmacytomas in the Setting of Newly Diagnosed Multiple Myeloma and Delayed Hemolytic Transfusion Reaction |
| title_full | Incidental Discovery of Multiorgan Extramedullary Plasmacytomas in the Setting of Newly Diagnosed Multiple Myeloma and Delayed Hemolytic Transfusion Reaction |
| title_fullStr | Incidental Discovery of Multiorgan Extramedullary Plasmacytomas in the Setting of Newly Diagnosed Multiple Myeloma and Delayed Hemolytic Transfusion Reaction |
| title_full_unstemmed | Incidental Discovery of Multiorgan Extramedullary Plasmacytomas in the Setting of Newly Diagnosed Multiple Myeloma and Delayed Hemolytic Transfusion Reaction |
| title_short | Incidental Discovery of Multiorgan Extramedullary Plasmacytomas in the Setting of Newly Diagnosed Multiple Myeloma and Delayed Hemolytic Transfusion Reaction |
| title_sort | incidental discovery of multiorgan extramedullary plasmacytomas in the setting of newly diagnosed multiple myeloma and delayed hemolytic transfusion reaction |
| url | http://dx.doi.org/10.1155/2017/4531858 |
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