Optimal control of vaccine distribution in a rabies metapopulation model

We consider an SIR metapopulation model for the spread of rabiesin raccoons. This system of ordinary differential equations considers subpop-ulations connected by movement. Vaccine for raccoons is distributed throughfood baits. We apply optimal control theory to find the best timing for dis-tributio...

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Main Authors: Erika Asano, Louis J. Gross, Suzanne Lenhart, Leslie A. Real
Format: Article
Language:English
Published: AIMS Press 2008-02-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.219
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author Erika Asano
Louis J. Gross
Suzanne Lenhart
Leslie A. Real
author_facet Erika Asano
Louis J. Gross
Suzanne Lenhart
Leslie A. Real
author_sort Erika Asano
collection DOAJ
description We consider an SIR metapopulation model for the spread of rabiesin raccoons. This system of ordinary differential equations considers subpop-ulations connected by movement. Vaccine for raccoons is distributed throughfood baits. We apply optimal control theory to find the best timing for dis-tribution of vaccine in each of the linked subpopulations across the landscape.This strategy is chosen to limit the disease optimally by making the numberof infections as small as possible while accounting for the cost of vaccination.
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spelling doaj-art-de6e1acc1a994b2aa174978a662a78612025-01-24T01:58:10ZengAIMS PressMathematical Biosciences and Engineering1551-00182008-02-015221923810.3934/mbe.2008.5.219Optimal control of vaccine distribution in a rabies metapopulation modelErika Asano0Louis J. Gross1Suzanne Lenhart2Leslie A. Real3Environmental Science, Policy and Geography, University of South Florida, St. Petersburg, FL 33701Environmental Science, Policy and Geography, University of South Florida, St. Petersburg, FL 33701Environmental Science, Policy and Geography, University of South Florida, St. Petersburg, FL 33701Environmental Science, Policy and Geography, University of South Florida, St. Petersburg, FL 33701We consider an SIR metapopulation model for the spread of rabiesin raccoons. This system of ordinary differential equations considers subpop-ulations connected by movement. Vaccine for raccoons is distributed throughfood baits. We apply optimal control theory to find the best timing for dis-tribution of vaccine in each of the linked subpopulations across the landscape.This strategy is chosen to limit the disease optimally by making the numberof infections as small as possible while accounting for the cost of vaccination.https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.219optimal controlvaccine.epidemiologymathematical modelrabies in raccoons
spellingShingle Erika Asano
Louis J. Gross
Suzanne Lenhart
Leslie A. Real
Optimal control of vaccine distribution in a rabies metapopulation model
Mathematical Biosciences and Engineering
optimal control
vaccine.
epidemiology
mathematical model
rabies in raccoons
title Optimal control of vaccine distribution in a rabies metapopulation model
title_full Optimal control of vaccine distribution in a rabies metapopulation model
title_fullStr Optimal control of vaccine distribution in a rabies metapopulation model
title_full_unstemmed Optimal control of vaccine distribution in a rabies metapopulation model
title_short Optimal control of vaccine distribution in a rabies metapopulation model
title_sort optimal control of vaccine distribution in a rabies metapopulation model
topic optimal control
vaccine.
epidemiology
mathematical model
rabies in raccoons
url https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.219
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AT suzannelenhart optimalcontrolofvaccinedistributioninarabiesmetapopulationmodel
AT leslieareal optimalcontrolofvaccinedistributioninarabiesmetapopulationmodel