Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association
Background. Data examining the association between obesity and erosive esophagitis (ErE) have been inconsistent, with very little known about interracial variation. Goals. To examine the association between obesity and ErE among patients of different ethnic/racial backgrounds. Methods. The study sam...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/7897390 |
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| author | Albin Abraham Seth Lipka Rabab Hajar Bhuma Krishnamachari Ravi Virdi Bobby Jacob Prakash Viswanathan Paul Mustacchia |
| author_facet | Albin Abraham Seth Lipka Rabab Hajar Bhuma Krishnamachari Ravi Virdi Bobby Jacob Prakash Viswanathan Paul Mustacchia |
| author_sort | Albin Abraham |
| collection | DOAJ |
| description | Background. Data examining the association between obesity and erosive esophagitis (ErE) have been inconsistent, with very little known about interracial variation. Goals. To examine the association between obesity and ErE among patients of different ethnic/racial backgrounds. Methods. The study sample included 2251 patients who underwent esophagogastroduodenoscopy (EGD). The effects of body mass index (BMI) on ErE were assessed by gender and in different ethnic groups. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariate logistic regression analysis. Results. The prevalence of ErE was 29.4% (661/2251). Overweight and obese subjects were significantly more likely to have ErE than individuals with a normal BMI, with the highest risk seen in the morbidly obese (OR 6.26; 95% CI 3.82–10.28; p<0.0001). Normal weight Black patients were less likely to have ErE as compared to Caucasians (OR 0.46; 95% CI 0.27–0.79; p=0.005), while the odds ratio comparing normal weight Hispanics to normal weight Whites was not statistically significant. No effect modification was seen between BMI and race/ethnicity or BMI and gender. Significant trends were seen in each gender and ethnicity. Conclusions. The effect of BMI on ErE does not appear to vary by race/ethnicity or gender. |
| format | Article |
| id | doaj-art-de516ddd059a49cbb387eec2bc50d0f4 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
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| series | Gastroenterology Research and Practice |
| spelling | doaj-art-de516ddd059a49cbb387eec2bc50d0f42025-02-03T05:58:51ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/78973907897390Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its AssociationAlbin Abraham0Seth Lipka1Rabab Hajar2Bhuma Krishnamachari3Ravi Virdi4Bobby Jacob5Prakash Viswanathan6Paul Mustacchia7Department of Gastroenterology, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Gastroenterology, Nassau University Medical Center, East Meadow, NY 11554, USAResearch Department, NYIT College of Osteopathic Medicine, Glen Head, NY 11545, USADepartment of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Gastroenterology, Nassau University Medical Center, East Meadow, NY 11554, USADepartment of Gastroenterology, Nassau University Medical Center, East Meadow, NY 11554, USABackground. Data examining the association between obesity and erosive esophagitis (ErE) have been inconsistent, with very little known about interracial variation. Goals. To examine the association between obesity and ErE among patients of different ethnic/racial backgrounds. Methods. The study sample included 2251 patients who underwent esophagogastroduodenoscopy (EGD). The effects of body mass index (BMI) on ErE were assessed by gender and in different ethnic groups. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariate logistic regression analysis. Results. The prevalence of ErE was 29.4% (661/2251). Overweight and obese subjects were significantly more likely to have ErE than individuals with a normal BMI, with the highest risk seen in the morbidly obese (OR 6.26; 95% CI 3.82–10.28; p<0.0001). Normal weight Black patients were less likely to have ErE as compared to Caucasians (OR 0.46; 95% CI 0.27–0.79; p=0.005), while the odds ratio comparing normal weight Hispanics to normal weight Whites was not statistically significant. No effect modification was seen between BMI and race/ethnicity or BMI and gender. Significant trends were seen in each gender and ethnicity. Conclusions. The effect of BMI on ErE does not appear to vary by race/ethnicity or gender.http://dx.doi.org/10.1155/2016/7897390 |
| spellingShingle | Albin Abraham Seth Lipka Rabab Hajar Bhuma Krishnamachari Ravi Virdi Bobby Jacob Prakash Viswanathan Paul Mustacchia Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association Gastroenterology Research and Practice |
| title | Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association |
| title_full | Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association |
| title_fullStr | Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association |
| title_full_unstemmed | Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association |
| title_short | Erosive Esophagitis in the Obese: The Effect of Ethnicity and Gender on Its Association |
| title_sort | erosive esophagitis in the obese the effect of ethnicity and gender on its association |
| url | http://dx.doi.org/10.1155/2016/7897390 |
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