Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions

Silent cerebral white matter lesions (WMLs) are a common finding on magnetic resonance imaging of the brain in the elderly. However, in patients with hypertension, WMLs tend to occur earlier in life and appear to be more severe. There is a body of evidence that supports the idea that WMLs in asympto...

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Main Author: Cristina Sierra
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.4061/2011/478710
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author Cristina Sierra
author_facet Cristina Sierra
author_sort Cristina Sierra
collection DOAJ
description Silent cerebral white matter lesions (WMLs) are a common finding on magnetic resonance imaging of the brain in the elderly. However, in patients with hypertension, WMLs tend to occur earlier in life and appear to be more severe. There is a body of evidence that supports the idea that WMLs in asymptomatic hypertensive patients should be considered a silent early marker of brain damage. It is known that ambulatory blood pressure monitoring (ABPM) correlates more closely with hypertension-related organ damage than office blood pressure. This paper focuses on the associations between blood pressure parameters obtained by 24-hour ABMP and cerebral WMLs.
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spelling doaj-art-de4e2b6fac0d4707b53fd87d847b9be22025-02-03T01:20:24ZengWileyInternational Journal of Hypertension2090-03922011-01-01201110.4061/2011/478710478710Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter LesionsCristina Sierra0Hypertension Unit, Department of Internal Medicine, Institute of Medicine and Dermatology, IDIBAPS, Hospital Clinic of Barcelona, University of Barcelona, Villarroel 170, 08036 Barcelona, SpainSilent cerebral white matter lesions (WMLs) are a common finding on magnetic resonance imaging of the brain in the elderly. However, in patients with hypertension, WMLs tend to occur earlier in life and appear to be more severe. There is a body of evidence that supports the idea that WMLs in asymptomatic hypertensive patients should be considered a silent early marker of brain damage. It is known that ambulatory blood pressure monitoring (ABPM) correlates more closely with hypertension-related organ damage than office blood pressure. This paper focuses on the associations between blood pressure parameters obtained by 24-hour ABMP and cerebral WMLs.http://dx.doi.org/10.4061/2011/478710
spellingShingle Cristina Sierra
Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions
International Journal of Hypertension
title Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions
title_full Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions
title_fullStr Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions
title_full_unstemmed Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions
title_short Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions
title_sort associations between ambulatory blood pressure parameters and cerebral white matter lesions
url http://dx.doi.org/10.4061/2011/478710
work_keys_str_mv AT cristinasierra associationsbetweenambulatorybloodpressureparametersandcerebralwhitematterlesions