Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study
ABSTRACT Background and Aims In the current study, we aimed to identify the association between major and minor electrocardiographic abnormalities and cardiovascular risk factors. Methods We used the Tehran cohort study baseline data, an ongoing multidisciplinary, longitudinal study designed to iden...
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Wiley
2025-01-01
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| Series: | Health Science Reports |
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| Online Access: | https://doi.org/10.1002/hsr2.70350 |
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| author | Pooria Ahmadi Sajjad Ahmadi‐Renani Parmida Sadat Pezeshki Sepehr Nayebirad Arash Jalali Akbar Shafiee Aryan Ayati Arian Afzalian Farshid Alaeddini Soheil Saadat Farzad Masoudkabir Ali Vasheghani‐Farahani Saeed Sadeghian Mohamamdali Boroumand Abbasali Karimi Boshra Pourbashash Kaveh Hosseini Frits R. Rosendaal |
| author_facet | Pooria Ahmadi Sajjad Ahmadi‐Renani Parmida Sadat Pezeshki Sepehr Nayebirad Arash Jalali Akbar Shafiee Aryan Ayati Arian Afzalian Farshid Alaeddini Soheil Saadat Farzad Masoudkabir Ali Vasheghani‐Farahani Saeed Sadeghian Mohamamdali Boroumand Abbasali Karimi Boshra Pourbashash Kaveh Hosseini Frits R. Rosendaal |
| author_sort | Pooria Ahmadi |
| collection | DOAJ |
| description | ABSTRACT Background and Aims In the current study, we aimed to identify the association between major and minor electrocardiographic abnormalities and cardiovascular risk factors. Methods We used the Tehran cohort study baseline data, an ongoing multidisciplinary, longitudinal study designed to identify cardiovascular disease risk factors in the adult population of Tehran. The electrocardiograms (ECGs) of 7630 Iranian adults aged 35 years and above were analyzed. ECG abnormalities were categorized into major or minor groups based on their clinical importance. Results were obtained by multivariable logistic regression and are expressed as odds ratios (ORs). Results A total of 756 (9.9%) participants had major ECG abnormalities, while minor abnormalities were detected in 2526 (33.1%). Males comprised 45.8% of the total population, and 41.8% of them had minor abnormalities. Individuals with older age, diabetes (OR = 1.35; 95% CI: 1.11–1.64), and hypertension (OR = 2.21; 95% CI: 1.82–2.68) had an increased risk of major ECG abnormalities. In contrast, intermediate (OR = 0.69; 95% CI: 0.57–0.84) and high physical activity levels (OR = 0.66; 95% CI: 0.51–0.86) were associated with a lower prevalence of major abnormalities. Male sex, older age, hypertension, and current smoking were also associated with an increased prevalence of ECG abnormalities combined (major or minor). Conclusion Major and minor ECG abnormalities are linked with important cardiovascular risk factors such as diabetes and hypertension. Since these abnormalities have been associated with poor outcomes, screening patients with cardiovascular risk factors with an ECG may distinguish high‐risk individuals who require appropriate care and follow‐up. |
| format | Article |
| id | doaj-art-de3ddbd81b6346388bb5193dbc0c2188 |
| institution | Kabale University |
| issn | 2398-8835 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj-art-de3ddbd81b6346388bb5193dbc0c21882025-01-29T03:42:39ZengWileyHealth Science Reports2398-88352025-01-0181n/an/a10.1002/hsr2.70350Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort StudyPooria Ahmadi0Sajjad Ahmadi‐Renani1Parmida Sadat Pezeshki2Sepehr Nayebirad3Arash Jalali4Akbar Shafiee5Aryan Ayati6Arian Afzalian7Farshid Alaeddini8Soheil Saadat9Farzad Masoudkabir10Ali Vasheghani‐Farahani11Saeed Sadeghian12Mohamamdali Boroumand13Abbasali Karimi14Boshra Pourbashash15Kaveh Hosseini16Frits R. Rosendaal17Department of Cardiology, Shariati Hospital, School of Medicine Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranDepartment of Emergency Medicine University of California, Irvine Irvine California USACardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranCardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranTehran Heart Center, Cardiovascular Diseases Research Institute Tehran University of Medical Sciences Tehran IranDepartment of Clinical Epidemiology Leiden University Medical Center Leiden The NetherlandsABSTRACT Background and Aims In the current study, we aimed to identify the association between major and minor electrocardiographic abnormalities and cardiovascular risk factors. Methods We used the Tehran cohort study baseline data, an ongoing multidisciplinary, longitudinal study designed to identify cardiovascular disease risk factors in the adult population of Tehran. The electrocardiograms (ECGs) of 7630 Iranian adults aged 35 years and above were analyzed. ECG abnormalities were categorized into major or minor groups based on their clinical importance. Results were obtained by multivariable logistic regression and are expressed as odds ratios (ORs). Results A total of 756 (9.9%) participants had major ECG abnormalities, while minor abnormalities were detected in 2526 (33.1%). Males comprised 45.8% of the total population, and 41.8% of them had minor abnormalities. Individuals with older age, diabetes (OR = 1.35; 95% CI: 1.11–1.64), and hypertension (OR = 2.21; 95% CI: 1.82–2.68) had an increased risk of major ECG abnormalities. In contrast, intermediate (OR = 0.69; 95% CI: 0.57–0.84) and high physical activity levels (OR = 0.66; 95% CI: 0.51–0.86) were associated with a lower prevalence of major abnormalities. Male sex, older age, hypertension, and current smoking were also associated with an increased prevalence of ECG abnormalities combined (major or minor). Conclusion Major and minor ECG abnormalities are linked with important cardiovascular risk factors such as diabetes and hypertension. Since these abnormalities have been associated with poor outcomes, screening patients with cardiovascular risk factors with an ECG may distinguish high‐risk individuals who require appropriate care and follow‐up.https://doi.org/10.1002/hsr2.70350cardiovascular diseasediabetesECGelectrocardiogramhypertension |
| spellingShingle | Pooria Ahmadi Sajjad Ahmadi‐Renani Parmida Sadat Pezeshki Sepehr Nayebirad Arash Jalali Akbar Shafiee Aryan Ayati Arian Afzalian Farshid Alaeddini Soheil Saadat Farzad Masoudkabir Ali Vasheghani‐Farahani Saeed Sadeghian Mohamamdali Boroumand Abbasali Karimi Boshra Pourbashash Kaveh Hosseini Frits R. Rosendaal Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study Health Science Reports cardiovascular disease diabetes ECG electrocardiogram hypertension |
| title | Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study |
| title_full | Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study |
| title_fullStr | Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study |
| title_full_unstemmed | Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study |
| title_short | Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study |
| title_sort | association of cardiovascular risk factors with major and minor electrocardiographic abnormalities a report from the cross sectional phase of tehran cohort study |
| topic | cardiovascular disease diabetes ECG electrocardiogram hypertension |
| url | https://doi.org/10.1002/hsr2.70350 |
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