Diabetes and Stroke Prevention: A Review
Stroke and diabetes mellitus are two separate conditions which share multiple common threads. Both are increasing in prevalence, both are diseases which affect blood vessels, and both are associated with other vascular risk factors, such as hypertension and dyslipidemia. Abnormal glucose regulation,...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Stroke Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2012/673187 |
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| _version_ | 1832553976646598656 |
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| author | Jonathan Hewitt Luis Castilla Guerra María del Carmen Fernández-Moreno Cristina Sierra |
| author_facet | Jonathan Hewitt Luis Castilla Guerra María del Carmen Fernández-Moreno Cristina Sierra |
| author_sort | Jonathan Hewitt |
| collection | DOAJ |
| description | Stroke and diabetes mellitus are two separate conditions which share multiple common threads. Both are increasing in prevalence, both are diseases which affect blood vessels, and both are associated with other vascular risk factors, such as hypertension and dyslipidemia. Abnormal glucose regulation, of which diabetes is one manifestation, is seen in up to two-thirds of people suffering from an acute stroke. Surprisingly, aggressive management of glucose after an acute stroke has not been shown to improve outcome or reduce the incidence of further strokes. More encouragingly, active management of other cardiovascular risk factors has been demonstrated to prevent stroke disease and improve outcome following a stroke in the diabetic person. Hypertension should be treated with a target of 140/80 mmHg, as a maximum. The drug of choice would be an ACE inhibitor, although the priority is blood pressure reduction regardless of the medication chosen. Lipids should be treated with a statin whatever the starting cholesterol. Antiplatelet treatment is also essential but there are no specific recommendations for the diabetic person. As these conditions become more prevalent it is imperative that the right treatment is offered for both primary and secondary prevention in diabetic people, in order to prevent disease and minimize disability. |
| format | Article |
| id | doaj-art-ddf9652959ab40b798416f03b15745d2 |
| institution | Kabale University |
| issn | 2090-8105 2042-0056 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stroke Research and Treatment |
| spelling | doaj-art-ddf9652959ab40b798416f03b15745d22025-02-03T05:52:45ZengWileyStroke Research and Treatment2090-81052042-00562012-01-01201210.1155/2012/673187673187Diabetes and Stroke Prevention: A ReviewJonathan Hewitt0Luis Castilla Guerra1María del Carmen Fernández-Moreno2Cristina Sierra3Geriatric Medicine, University of Cardiff, Cardiff CF14 4XY, UKDepartment of Internal Medicine, Hospital de la Merced, University of Seville, Seville, SpainDepartment of Neurology, Hospital de Valme, University of Seville, Seville, SpainDepartment of Internal Medicine, Hospital Clinic, University of Barcelona, Barcelona, SpainStroke and diabetes mellitus are two separate conditions which share multiple common threads. Both are increasing in prevalence, both are diseases which affect blood vessels, and both are associated with other vascular risk factors, such as hypertension and dyslipidemia. Abnormal glucose regulation, of which diabetes is one manifestation, is seen in up to two-thirds of people suffering from an acute stroke. Surprisingly, aggressive management of glucose after an acute stroke has not been shown to improve outcome or reduce the incidence of further strokes. More encouragingly, active management of other cardiovascular risk factors has been demonstrated to prevent stroke disease and improve outcome following a stroke in the diabetic person. Hypertension should be treated with a target of 140/80 mmHg, as a maximum. The drug of choice would be an ACE inhibitor, although the priority is blood pressure reduction regardless of the medication chosen. Lipids should be treated with a statin whatever the starting cholesterol. Antiplatelet treatment is also essential but there are no specific recommendations for the diabetic person. As these conditions become more prevalent it is imperative that the right treatment is offered for both primary and secondary prevention in diabetic people, in order to prevent disease and minimize disability.http://dx.doi.org/10.1155/2012/673187 |
| spellingShingle | Jonathan Hewitt Luis Castilla Guerra María del Carmen Fernández-Moreno Cristina Sierra Diabetes and Stroke Prevention: A Review Stroke Research and Treatment |
| title | Diabetes and Stroke Prevention: A Review |
| title_full | Diabetes and Stroke Prevention: A Review |
| title_fullStr | Diabetes and Stroke Prevention: A Review |
| title_full_unstemmed | Diabetes and Stroke Prevention: A Review |
| title_short | Diabetes and Stroke Prevention: A Review |
| title_sort | diabetes and stroke prevention a review |
| url | http://dx.doi.org/10.1155/2012/673187 |
| work_keys_str_mv | AT jonathanhewitt diabetesandstrokepreventionareview AT luiscastillaguerra diabetesandstrokepreventionareview AT mariadelcarmenfernandezmoreno diabetesandstrokepreventionareview AT cristinasierra diabetesandstrokepreventionareview |