Magnetic core‐shell Fe3O4@TiO2 nanocomposites for broad spectrum antibacterial applications
Abstract The authors have synthesised a core‐shell Fe3O4@TiO2 nanocomposite consisting of Fe3O4 as a magnetic core, and TiO2 as its external shell. The TiO2 shell is primarily intended for use as a biocompatible and antimicrobial carrier for drug delivery and possible other applications such as wast...
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| Format: | Article |
| Language: | English |
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Wiley
2021-05-01
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| Series: | IET Nanobiotechnology |
| Online Access: | https://doi.org/10.1049/nbt2.12017 |
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| author | Nisha Rani Brijnandan S. Dehiya |
| author_facet | Nisha Rani Brijnandan S. Dehiya |
| author_sort | Nisha Rani |
| collection | DOAJ |
| description | Abstract The authors have synthesised a core‐shell Fe3O4@TiO2 nanocomposite consisting of Fe3O4 as a magnetic core, and TiO2 as its external shell. The TiO2 shell is primarily intended for use as a biocompatible and antimicrobial carrier for drug delivery and possible other applications such as wastewater remediation purposes because of its known antibacterial and photocatalytic properties. The magnetic core enables quick and easy concentration and separation of nanoparticles. The magnetite nanoparticles were synthesized by a hydrothermal route using ferric chloride as a single‐source precursor. The magnetite nanoparticles were then coated with titanium dioxide using titanium butoxide as a precursor. The core‐shell Fe3O4@TiO2 nanostructure particles were characterized by XRD, UV spectroscopy, and FT‐IR, TEM, and VSM techniques. The saturation magnetization of Fe3O4 nanoparticles was significantly reduced from 74.2 to 13.7 emu/g after the TiO2 coating. The antibacterial studies of magnetic nanoparticles and the titania‐coated magnetic nanocomposite were carried out against gram+ve, and gram–ve bacteria (Staphylococcus aureus, Pseudomonas aeruginosa, Shigella flexneri, Escherichia coli, and Salmonella typhi) using well diffusion technique. The inhibition zone for E. coli (17 mm after 24 h) was higher than the other bacterial strains; nevertheless, both the uncoated and TiO2‐coated magnetite nanocomposites showed admirable antibacterial activity against each of the above bacterial strains. |
| format | Article |
| id | doaj-art-dde8ba1df8c04e658b0b74d3e47fa15e |
| institution | Kabale University |
| issn | 1751-8741 1751-875X |
| language | English |
| publishDate | 2021-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | IET Nanobiotechnology |
| spelling | doaj-art-dde8ba1df8c04e658b0b74d3e47fa15e2025-02-03T06:47:18ZengWileyIET Nanobiotechnology1751-87411751-875X2021-05-0115330130810.1049/nbt2.12017Magnetic core‐shell Fe3O4@TiO2 nanocomposites for broad spectrum antibacterial applicationsNisha Rani0Brijnandan S. Dehiya1Department of (MSN) Materials Science and Nanotechnology Deenbandhu Chhotu Ram University of Science and Technology (DCRUST) Murthal Haryana IndiaDepartment of (MSN) Materials Science and Nanotechnology Deenbandhu Chhotu Ram University of Science and Technology (DCRUST) Murthal Haryana IndiaAbstract The authors have synthesised a core‐shell Fe3O4@TiO2 nanocomposite consisting of Fe3O4 as a magnetic core, and TiO2 as its external shell. The TiO2 shell is primarily intended for use as a biocompatible and antimicrobial carrier for drug delivery and possible other applications such as wastewater remediation purposes because of its known antibacterial and photocatalytic properties. The magnetic core enables quick and easy concentration and separation of nanoparticles. The magnetite nanoparticles were synthesized by a hydrothermal route using ferric chloride as a single‐source precursor. The magnetite nanoparticles were then coated with titanium dioxide using titanium butoxide as a precursor. The core‐shell Fe3O4@TiO2 nanostructure particles were characterized by XRD, UV spectroscopy, and FT‐IR, TEM, and VSM techniques. The saturation magnetization of Fe3O4 nanoparticles was significantly reduced from 74.2 to 13.7 emu/g after the TiO2 coating. The antibacterial studies of magnetic nanoparticles and the titania‐coated magnetic nanocomposite were carried out against gram+ve, and gram–ve bacteria (Staphylococcus aureus, Pseudomonas aeruginosa, Shigella flexneri, Escherichia coli, and Salmonella typhi) using well diffusion technique. The inhibition zone for E. coli (17 mm after 24 h) was higher than the other bacterial strains; nevertheless, both the uncoated and TiO2‐coated magnetite nanocomposites showed admirable antibacterial activity against each of the above bacterial strains.https://doi.org/10.1049/nbt2.12017 |
| spellingShingle | Nisha Rani Brijnandan S. Dehiya Magnetic core‐shell Fe3O4@TiO2 nanocomposites for broad spectrum antibacterial applications IET Nanobiotechnology |
| title | Magnetic core‐shell Fe3O4@TiO2 nanocomposites for broad spectrum antibacterial applications |
| title_full | Magnetic core‐shell Fe3O4@TiO2 nanocomposites for broad spectrum antibacterial applications |
| title_fullStr | Magnetic core‐shell Fe3O4@TiO2 nanocomposites for broad spectrum antibacterial applications |
| title_full_unstemmed | Magnetic core‐shell Fe3O4@TiO2 nanocomposites for broad spectrum antibacterial applications |
| title_short | Magnetic core‐shell Fe3O4@TiO2 nanocomposites for broad spectrum antibacterial applications |
| title_sort | magnetic core shell fe3o4 tio2 nanocomposites for broad spectrum antibacterial applications |
| url | https://doi.org/10.1049/nbt2.12017 |
| work_keys_str_mv | AT nisharani magneticcoreshellfe3o4tio2nanocompositesforbroadspectrumantibacterialapplications AT brijnandansdehiya magneticcoreshellfe3o4tio2nanocompositesforbroadspectrumantibacterialapplications |