The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension

The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension

Abstract The Tad (Tight adherence) pilus is a bacterial appendage implicated in virulence, cell-cell aggregation, and biofilm formation. Despite its homology to the well-characterised Type IV pilus, the structure and assembly mechanism of the Tad pilus are poorly understood. Here, we investigate the...

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Main Authors: Sasha L. Evans, Iryna Peretiazhko, Sahil Y. Karnani, Lindsey S. Marmont, James H. R. Wheeler, Boo Shan Tseng, William M. Durham, John C. Whitney, Julien R. C. Bergeron
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62457-8
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