An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli

An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli

All living organisms have developed strategies to respond to chromosomal damage and preserve genome integrity. One such response is the repair of DNA double-strand breaks (DSBs), one of the most toxic forms of DNA lesions. In Escherichia coli, DSBs are repaired via RecBCD-dependent homologous recomb...

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Bibliographic Details
Main Authors: Irina Kalita, Ira Alexandra Iosub, Lorna McLaren, Louise Goossens, Sander Granneman, Meriem El Karoui
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-08-01
Series:eLife
Subjects:
RecBCD enzyme
DNA repair
Hfq protein
post-transcriptional regulation
noise suppression
Online Access:https://elifesciences.org/articles/94918
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