Infantile Cortical Hyperostosis: Report of a Case with Observations on Clinical Manifestations, Radiology, and Pathology with a Late Follow-Up of Eight Years
Purpose. The purpose of our study was to investigate clinical manifestations, roentgen images, histopathological studies, and evolution of the disease in patient displaying infantile cortical hyperostosis. Methods. Roentgenograms were made to evaluate a neonatal patient presenting multiple soft-tiss...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2016/2073854 |
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| author | Pedro Carlos M. Sarmento Pinheiro Ierecê Lins Aymore Armando Rocha Amoedo Paulo Miguel Hemais |
| author_facet | Pedro Carlos M. Sarmento Pinheiro Ierecê Lins Aymore Armando Rocha Amoedo Paulo Miguel Hemais |
| author_sort | Pedro Carlos M. Sarmento Pinheiro |
| collection | DOAJ |
| description | Purpose. The purpose of our study was to investigate clinical manifestations, roentgen images, histopathological studies, and evolution of the disease in patient displaying infantile cortical hyperostosis. Methods. Roentgenograms were made to evaluate a neonatal patient presenting multiple soft-tissue swellings. The initial radiographs insinuated that the disease had been present for some time in utero. Bone puncture biopsy of the tibia for histopathological observation and diagnosis conclusions was performed. Results. The disease was demonstrated radiographically by massive cortical diaphyseal thickening and also extensive periosteal new bone formation surrounding several bones. Results in blood count were as follows: discrete anemia, moderate leukocytosis, and elevated sedimentation rate. Histological pattern of tissue removed from tibia showed lamellar cortical bones and hyperplasia. Biopsy studies disclosed no evidence of neoplasia as well as of bacterial infection. Comments. Clinical manifestations in a neonatal patient displaying infantile cortical hyperostosis have gradually decreased. Radiograph findings have demonstrated complete recovery of bones manifested by the disease. The pathologic findings are in accordance with previous microscopic examination summarized by the literature. Total patient cure, without sequels, could be demonstrated. |
| format | Article |
| id | doaj-art-dd885aecda1a4ef88d5aa6e1b553c546 |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-dd885aecda1a4ef88d5aa6e1b553c5462025-02-03T01:00:56ZengWileyCase Reports in Pediatrics2090-68032090-68112016-01-01201610.1155/2016/20738542073854Infantile Cortical Hyperostosis: Report of a Case with Observations on Clinical Manifestations, Radiology, and Pathology with a Late Follow-Up of Eight YearsPedro Carlos M. Sarmento Pinheiro0Ierecê Lins Aymore1Armando Rocha Amoedo2Paulo Miguel Hemais3Orthopedic Department, Jesus Children’s Hospital, Rio de Janeiro, RJ, BrazilOncological and Pathological Department of National Institute of Orthopedic and Traumatology (INTO), Rio de Janeiro, RJ, BrazilRadiological Department, Jesus Children’s Hospital, Rio de Janeiro, RJ, BrazilDepartment of Radiology, National Institute of Orthopedic and Traumatology (INTO), Rio de Janeiro, RJ, BrazilPurpose. The purpose of our study was to investigate clinical manifestations, roentgen images, histopathological studies, and evolution of the disease in patient displaying infantile cortical hyperostosis. Methods. Roentgenograms were made to evaluate a neonatal patient presenting multiple soft-tissue swellings. The initial radiographs insinuated that the disease had been present for some time in utero. Bone puncture biopsy of the tibia for histopathological observation and diagnosis conclusions was performed. Results. The disease was demonstrated radiographically by massive cortical diaphyseal thickening and also extensive periosteal new bone formation surrounding several bones. Results in blood count were as follows: discrete anemia, moderate leukocytosis, and elevated sedimentation rate. Histological pattern of tissue removed from tibia showed lamellar cortical bones and hyperplasia. Biopsy studies disclosed no evidence of neoplasia as well as of bacterial infection. Comments. Clinical manifestations in a neonatal patient displaying infantile cortical hyperostosis have gradually decreased. Radiograph findings have demonstrated complete recovery of bones manifested by the disease. The pathologic findings are in accordance with previous microscopic examination summarized by the literature. Total patient cure, without sequels, could be demonstrated.http://dx.doi.org/10.1155/2016/2073854 |
| spellingShingle | Pedro Carlos M. Sarmento Pinheiro Ierecê Lins Aymore Armando Rocha Amoedo Paulo Miguel Hemais Infantile Cortical Hyperostosis: Report of a Case with Observations on Clinical Manifestations, Radiology, and Pathology with a Late Follow-Up of Eight Years Case Reports in Pediatrics |
| title | Infantile Cortical Hyperostosis: Report of a Case with Observations on Clinical Manifestations, Radiology, and Pathology with a Late Follow-Up of Eight Years |
| title_full | Infantile Cortical Hyperostosis: Report of a Case with Observations on Clinical Manifestations, Radiology, and Pathology with a Late Follow-Up of Eight Years |
| title_fullStr | Infantile Cortical Hyperostosis: Report of a Case with Observations on Clinical Manifestations, Radiology, and Pathology with a Late Follow-Up of Eight Years |
| title_full_unstemmed | Infantile Cortical Hyperostosis: Report of a Case with Observations on Clinical Manifestations, Radiology, and Pathology with a Late Follow-Up of Eight Years |
| title_short | Infantile Cortical Hyperostosis: Report of a Case with Observations on Clinical Manifestations, Radiology, and Pathology with a Late Follow-Up of Eight Years |
| title_sort | infantile cortical hyperostosis report of a case with observations on clinical manifestations radiology and pathology with a late follow up of eight years |
| url | http://dx.doi.org/10.1155/2016/2073854 |
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