Granulomatous prostatitis mimicking prostate cancer in a patient with psoriatic arthritis: a case report

Granulomatous prostatitis (GP) is an unusual and benign inflammatory condition of the prostate, where autoimmunity has been recognized as a key factor in the pathogenesis of GP in a subset of patients. Clinically, GP poses diagnostic challenges as it may strongly mimic prostate cancer from a clinica...

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Bibliographic Details
Main Authors: Luigi De Luca, Felice Crocetto, Biagio Barone, Massimiliano Creta, Salvatore Pesce, Achille Aveta, Maria Raffaela Campanino, Ciro Imbimbo, Nicola Longo
Format: Article
Language:English
Published: Taylor & Francis Group 2020-08-01
Series:Future Science OA
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Online Access:https://www.future-science.com/doi/10.2144/fsoa-2020-0031
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Summary:Granulomatous prostatitis (GP) is an unusual and benign inflammatory condition of the prostate, where autoimmunity has been recognized as a key factor in the pathogenesis of GP in a subset of patients. Clinically, GP poses diagnostic challenges as it may strongly mimic prostate cancer from a clinical, biochemical and radiological point of view. The occurrence of GP in patients suffering from psoriasis, a systemic autoimmune disease, has never been investigated. We describe the case of GP in a patient with psoriatic arthritis presenting with an increased prostate specific antigen level, and evidence of a nodular lesion visualized by prostate multiparametric magnetic resonance imaging, which was highly suspicious for aggressive prostate cancer.
ISSN:2056-5623