Microbial diversity and composition in the gut microbiome of patients during systemic inflammatory response syndrome: can we use gut bacteria as potential biomarkers to characterize sepsis?

Microbial diversity and composition in the gut microbiome of patients during systemic inflammatory response syndrome: can we use gut bacteria as potential biomarkers to characterize sepsis?

BackgroundCritically ill patients, including those with systemic inflammatory response syndrome (SIRS) and sepsis, frequently exhibit gut microbiota disruption due to physiological stress and broad-spectrum antimicrobial therapy (AT). Although antibiotics are essential for controlling infection, the...

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Main Authors: Rafaela Ramalho Guerra, Patricia da Silva Fernandes, Otávio von Ameln Lovison, Giovanna de Ross Forni, Gabriel Silva de Oliveira, Luana Cristina Viana, Dariane Castro Pereira, William Latosinski Matos, Miriane Melo Silveira Moretti, Fabiana Zempulski Volpato, Luciana Giordani, Patricia Orlandi Barth, Tarsila Vieceli, Diego Rodrigues Falci, Márcio Manozzo Boniatti, Afonso Luís Barth, Andreza Francisco Martins
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
amplicon sequencing
biomarker
gut microbiota
sepsis
SIRS
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1622866/full
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