Mast Cell-Mediated Inhibition of Abdominal Neutrophil Inflammation by a PEGylated TLR7 Ligand
Although the mechanisms for sustained chemokine gradients and recurring cell infiltration in sterile peritonitis have not been elucidated, toll-like receptors (TLRs) have been implicated. To abate the deleterious recruitment of neutrophils in sterile inflammation, we repeatedly administered a TLR7 l...
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Main Authors: | Tomoko Hayashi, Shiyin Yao, Brian Crain, Michael Chan, Howard B. Cottam, Fitzgerald Lao, Dennis A. Carson, Maripat Corr |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2012/262394 |
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