Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary
The role of infection in the etiology of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is poorly understood. Large-scale epidemiological descriptions of the histology and microbiology of BRONJ are not found in the literature. Herein, we present a systematic review of BRONJ histology and mi...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2014/452737 |
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| _version_ | 1832550382833762304 |
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| author | A. M. Hinson C. W. Smith E. R. Siegel B. C. Stack |
| author_facet | A. M. Hinson C. W. Smith E. R. Siegel B. C. Stack |
| author_sort | A. M. Hinson |
| collection | DOAJ |
| description | The role of infection in the etiology of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is poorly understood. Large-scale epidemiological descriptions of the histology and microbiology of BRONJ are not found in the literature. Herein, we present a systematic review of BRONJ histology and microbiology (including demographics, immunocompromised associations, clinical signs and symptoms, disease severity, antibiotic and surgical treatments, and recovery status) validating that infection should still be considered a prime component in the multifactorial disease. |
| format | Article |
| id | doaj-art-dd4fffc2f1174d6aa7982594568df25a |
| institution | Kabale University |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-dd4fffc2f1174d6aa7982594568df25a2025-02-03T06:06:57ZengWileyInternational Journal of Dentistry1687-87281687-87362014-01-01201410.1155/2014/452737452737Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year SummaryA. M. Hinson0C. W. Smith1E. R. Siegel2B. C. Stack3University of Arkansas for Medical Sciences (UAMS), College of Medicine, Little Rock, AR 72205, USADepartment of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USADepartment of Biostatistics, UAMS, Little Rock, AR 72205, USADepartment of Otolaryngology-Head and Neck Surgery, UAMS, 4301 W. Markham Street No. 543, Little Rock, AR 72205, USAThe role of infection in the etiology of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is poorly understood. Large-scale epidemiological descriptions of the histology and microbiology of BRONJ are not found in the literature. Herein, we present a systematic review of BRONJ histology and microbiology (including demographics, immunocompromised associations, clinical signs and symptoms, disease severity, antibiotic and surgical treatments, and recovery status) validating that infection should still be considered a prime component in the multifactorial disease.http://dx.doi.org/10.1155/2014/452737 |
| spellingShingle | A. M. Hinson C. W. Smith E. R. Siegel B. C. Stack Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary International Journal of Dentistry |
| title | Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary |
| title_full | Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary |
| title_fullStr | Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary |
| title_full_unstemmed | Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary |
| title_short | Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary |
| title_sort | is bisphosphonate related osteonecrosis of the jaw an infection a histological and microbiological ten year summary |
| url | http://dx.doi.org/10.1155/2014/452737 |
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