An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature
Abstract Background Central giant cell granulomas are benign tumours of the mandible, presenting in children and young adults. Divided into non- and aggressive subtypes, the aggressive subtype is relatively rare and can occasionally progress rapidly, resulting in significant morbidity. Case presenta...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2019-07-01
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| Series: | Journal of Otolaryngology - Head and Neck Surgery |
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| Online Access: | http://link.springer.com/article/10.1186/s40463-019-0356-5 |
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| author | Yiqiao Wang Andre Le Dina El Demellawy Mary Shago Michael Odell Stephanie Johnson-Obaseki |
| author_facet | Yiqiao Wang Andre Le Dina El Demellawy Mary Shago Michael Odell Stephanie Johnson-Obaseki |
| author_sort | Yiqiao Wang |
| collection | DOAJ |
| description | Abstract Background Central giant cell granulomas are benign tumours of the mandible, presenting in children and young adults. Divided into non- and aggressive subtypes, the aggressive subtype is relatively rare and can occasionally progress rapidly, resulting in significant morbidity. Case presentation We present a case of an aggressive central giant cell granuloma (CGCG) in a six year-old female. The lesion originated in the right mandibular ramus and progressed rapidly to involve the condyle. Diagnosis was made using a combination of imaging and pathology. A timely en bloc resection of the hemi-mandible was performed with placement of a reconstructive titanium plate and condylar prosthesis. Conclusion Our case demonstrates the importance of considering CGCG in the differential diagnosis of rapidly progressive mandibular lesions in the pediatric population. Prompt diagnosis and management can greatly improve long-term outcomes. |
| format | Article |
| id | doaj-art-dd4fb83c6d6d4b18b5cf1a932853c87b |
| institution | Kabale University |
| issn | 1916-0216 |
| language | English |
| publishDate | 2019-07-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Otolaryngology - Head and Neck Surgery |
| spelling | doaj-art-dd4fb83c6d6d4b18b5cf1a932853c87b2025-02-03T10:55:01ZengSAGE PublishingJournal of Otolaryngology - Head and Neck Surgery1916-02162019-07-014811710.1186/s40463-019-0356-5An aggressive central giant cell granuloma in a pediatric patient: case report and review of literatureYiqiao Wang0Andre Le1Dina El Demellawy2Mary Shago3Michael Odell4Stephanie Johnson-Obaseki5Faculty of Medicine, University of OttawaDepartment of Otolaryngology – Head and Neck Surgery, Faculty of Medicine, University of OttawaDepartment of Pathology, Children’s Hospital of Eastern Ontario, Faculty of Medicine, University of OttawaDepartment of Paediatric Laboratory Medicine, The Hospital for Sick ChildrenDepartment of Otolaryngology – Head and Neck Surgery, Faculty of Medicine, University of OttawaDepartment of Otolaryngology – Head and Neck Surgery, Faculty of Medicine, University of OttawaAbstract Background Central giant cell granulomas are benign tumours of the mandible, presenting in children and young adults. Divided into non- and aggressive subtypes, the aggressive subtype is relatively rare and can occasionally progress rapidly, resulting in significant morbidity. Case presentation We present a case of an aggressive central giant cell granuloma (CGCG) in a six year-old female. The lesion originated in the right mandibular ramus and progressed rapidly to involve the condyle. Diagnosis was made using a combination of imaging and pathology. A timely en bloc resection of the hemi-mandible was performed with placement of a reconstructive titanium plate and condylar prosthesis. Conclusion Our case demonstrates the importance of considering CGCG in the differential diagnosis of rapidly progressive mandibular lesions in the pediatric population. Prompt diagnosis and management can greatly improve long-term outcomes.http://link.springer.com/article/10.1186/s40463-019-0356-5Central giant cell granulomaMandibleAggressivePediatrics |
| spellingShingle | Yiqiao Wang Andre Le Dina El Demellawy Mary Shago Michael Odell Stephanie Johnson-Obaseki An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature Journal of Otolaryngology - Head and Neck Surgery Central giant cell granuloma Mandible Aggressive Pediatrics |
| title | An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature |
| title_full | An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature |
| title_fullStr | An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature |
| title_full_unstemmed | An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature |
| title_short | An aggressive central giant cell granuloma in a pediatric patient: case report and review of literature |
| title_sort | aggressive central giant cell granuloma in a pediatric patient case report and review of literature |
| topic | Central giant cell granuloma Mandible Aggressive Pediatrics |
| url | http://link.springer.com/article/10.1186/s40463-019-0356-5 |
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