There May Be a Way to Say 'NO' to Gastric Injury Associated with the Combined Use of Aspirin and Cyclooxygenase-2 Inhibitors

Due to evidence that it reduces the frequency of cardiac events and stroke, the use of daily low-dose aspirin has dramatically increased over the past 20 years (1). The use of other nonsteroidal anti-inflammatory drugs (NSAIDs) for the relief of pain and inflammation has also increased (2). Unf...

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Main Authors: Jennifer J Williams, Paul L Beck
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2004/841412
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author Jennifer J Williams
Paul L Beck
author_facet Jennifer J Williams
Paul L Beck
author_sort Jennifer J Williams
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description Due to evidence that it reduces the frequency of cardiac events and stroke, the use of daily low-dose aspirin has dramatically increased over the past 20 years (1). The use of other nonsteroidal anti-inflammatory drugs (NSAIDs) for the relief of pain and inflammation has also increased (2). Unfortunately, aspirin and conventional NSAIDs such as diclofenac are notorious for causing significant damage to the upper gastrointestinal tract because they suppress prostaglandin (PG) synthesis (3).
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spelling doaj-art-dd1f4a2610674c9393166e4dfce3e2832025-02-03T01:29:05ZengWileyCanadian Journal of Gastroenterology0835-79002004-01-01181169769810.1155/2004/841412There May Be a Way to Say 'NO' to Gastric Injury Associated with the Combined Use of Aspirin and Cyclooxygenase-2 InhibitorsJennifer J WilliamsPaul L BeckDue to evidence that it reduces the frequency of cardiac events and stroke, the use of daily low-dose aspirin has dramatically increased over the past 20 years (1). The use of other nonsteroidal anti-inflammatory drugs (NSAIDs) for the relief of pain and inflammation has also increased (2). Unfortunately, aspirin and conventional NSAIDs such as diclofenac are notorious for causing significant damage to the upper gastrointestinal tract because they suppress prostaglandin (PG) synthesis (3).http://dx.doi.org/10.1155/2004/841412
spellingShingle Jennifer J Williams
Paul L Beck
There May Be a Way to Say 'NO' to Gastric Injury Associated with the Combined Use of Aspirin and Cyclooxygenase-2 Inhibitors
Canadian Journal of Gastroenterology
title There May Be a Way to Say 'NO' to Gastric Injury Associated with the Combined Use of Aspirin and Cyclooxygenase-2 Inhibitors
title_full There May Be a Way to Say 'NO' to Gastric Injury Associated with the Combined Use of Aspirin and Cyclooxygenase-2 Inhibitors
title_fullStr There May Be a Way to Say 'NO' to Gastric Injury Associated with the Combined Use of Aspirin and Cyclooxygenase-2 Inhibitors
title_full_unstemmed There May Be a Way to Say 'NO' to Gastric Injury Associated with the Combined Use of Aspirin and Cyclooxygenase-2 Inhibitors
title_short There May Be a Way to Say 'NO' to Gastric Injury Associated with the Combined Use of Aspirin and Cyclooxygenase-2 Inhibitors
title_sort there may be a way to say no to gastric injury associated with the combined use of aspirin and cyclooxygenase 2 inhibitors
url http://dx.doi.org/10.1155/2004/841412
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AT paullbeck theremaybeawaytosaynotogastricinjuryassociatedwiththecombineduseofaspirinandcyclooxygenase2inhibitors