Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United States

Detecting and responding to clusters of rapid HIV transmission is a core HIV prevention strategy in the United States, guiding public health interventions and identifying gaps in prevention and care services. In 2016, the Centers for Disease Control and Prevention (CDC) initiated molecular cluster...

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Main Authors: Anne Marie France, Camden J. Hallmark, Nivedha Panneer, Rachael Billock, Olivia O. Russell, Mary Plaster, Jessica Alberti, Fathima Nuthan, Neeraja Saduvala, David Philpott, M. Cheryl Bañez Ocfemia, Scott Cope, Angela L. Hernandez, Sergei L. Kosakovsky Pond, Joel O. Wertheim, Steven Weaver, Saja Khader, Kevin Johnson, Alexandra M. Oster
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2025-05-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/31/13/24-1143_article
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author Anne Marie France
Camden J. Hallmark
Nivedha Panneer
Rachael Billock
Olivia O. Russell
Mary Plaster
Jessica Alberti
Fathima Nuthan
Neeraja Saduvala
David Philpott
M. Cheryl Bañez Ocfemia
Scott Cope
Angela L. Hernandez
Sergei L. Kosakovsky Pond
Joel O. Wertheim
Steven Weaver
Saja Khader
Kevin Johnson
Alexandra M. Oster
author_facet Anne Marie France
Camden J. Hallmark
Nivedha Panneer
Rachael Billock
Olivia O. Russell
Mary Plaster
Jessica Alberti
Fathima Nuthan
Neeraja Saduvala
David Philpott
M. Cheryl Bañez Ocfemia
Scott Cope
Angela L. Hernandez
Sergei L. Kosakovsky Pond
Joel O. Wertheim
Steven Weaver
Saja Khader
Kevin Johnson
Alexandra M. Oster
author_sort Anne Marie France
collection DOAJ
description Detecting and responding to clusters of rapid HIV transmission is a core HIV prevention strategy in the United States, guiding public health interventions and identifying gaps in prevention and care services. In 2016, the Centers for Disease Control and Prevention (CDC) initiated molecular cluster detection using data from 27 jurisdictions. During 2016–2023, CDC expanded sequence reporting nationwide and deployed Secure HIV-TRACE, an application supporting health department (HD) molecular cluster detection. CDC conducts molecular cluster detection quarterly; state and local HDs analyze local data monthly. HDs began routinely reporting clusters to CDC by using cluster report forms in 2020. During 2018–2023, CDC identified 404 molecular clusters of rapid HIV transmission; 325 (80%) involved multiple jurisdictions. During 2020–2023, HDs reported 298 molecular clusters to CDC; 249 were first detected by HDs. Expanding molecular cluster detection has provided a foundation for improving service delivery to networks experiencing rapid HIV transmission.
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publishDate 2025-05-01
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series Emerging Infectious Diseases
spelling doaj-art-dd0a5be85b2d4e939ba4d90d6f44fa132025-08-20T03:49:36ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592025-05-013113808810.3201/eid3113.241143Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United StatesAnne Marie FranceCamden J. HallmarkNivedha PanneerRachael BillockOlivia O. RussellMary PlasterJessica AlbertiFathima NuthanNeeraja SaduvalaDavid PhilpottM. Cheryl Bañez OcfemiaScott CopeAngela L. HernandezSergei L. Kosakovsky PondJoel O. WertheimSteven WeaverSaja KhaderKevin JohnsonAlexandra M. Oster Detecting and responding to clusters of rapid HIV transmission is a core HIV prevention strategy in the United States, guiding public health interventions and identifying gaps in prevention and care services. In 2016, the Centers for Disease Control and Prevention (CDC) initiated molecular cluster detection using data from 27 jurisdictions. During 2016–2023, CDC expanded sequence reporting nationwide and deployed Secure HIV-TRACE, an application supporting health department (HD) molecular cluster detection. CDC conducts molecular cluster detection quarterly; state and local HDs analyze local data monthly. HDs began routinely reporting clusters to CDC by using cluster report forms in 2020. During 2018–2023, CDC identified 404 molecular clusters of rapid HIV transmission; 325 (80%) involved multiple jurisdictions. During 2020–2023, HDs reported 298 molecular clusters to CDC; 249 were first detected by HDs. Expanding molecular cluster detection has provided a foundation for improving service delivery to networks experiencing rapid HIV transmission. https://wwwnc.cdc.gov/eid/article/31/13/24-1143_articleHIVmolecular clusterHIV transmissionmolecular epidemiologyoutbreak detectionHIV/AIDS and other retroviruses
spellingShingle Anne Marie France
Camden J. Hallmark
Nivedha Panneer
Rachael Billock
Olivia O. Russell
Mary Plaster
Jessica Alberti
Fathima Nuthan
Neeraja Saduvala
David Philpott
M. Cheryl Bañez Ocfemia
Scott Cope
Angela L. Hernandez
Sergei L. Kosakovsky Pond
Joel O. Wertheim
Steven Weaver
Saja Khader
Kevin Johnson
Alexandra M. Oster
Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United States
Emerging Infectious Diseases
HIV
molecular cluster
HIV transmission
molecular epidemiology
outbreak detection
HIV/AIDS and other retroviruses
title Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United States
title_full Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United States
title_fullStr Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United States
title_full_unstemmed Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United States
title_short Nationwide Implementation of HIV Molecular Cluster Detection by Centers for Disease Control and Prevention and State and Local Health Departments, United States
title_sort nationwide implementation of hiv molecular cluster detection by centers for disease control and prevention and state and local health departments united states
topic HIV
molecular cluster
HIV transmission
molecular epidemiology
outbreak detection
HIV/AIDS and other retroviruses
url https://wwwnc.cdc.gov/eid/article/31/13/24-1143_article
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