Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol
BackgroundLow back pain and lower extremity sensory and functional abnormalities are common symptoms of lumbar disc herniation (LDH), which can easily cause walking dysfunction and significantly impair the quality of life of patients. Tuina and traditional Chinese exercises (TCEs) are effective in r...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2025.1497933/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832589943870849024 |
|---|---|
| author | Zhihong Fan Shenghong Jia Xin Zhou Chao Li Jiahao Shao Xiaofeng Liu Yitao Liao Yenan Xu Dandan He Shixiang Wu Xian Zhang |
| author_facet | Zhihong Fan Shenghong Jia Xin Zhou Chao Li Jiahao Shao Xiaofeng Liu Yitao Liao Yenan Xu Dandan He Shixiang Wu Xian Zhang |
| author_sort | Zhihong Fan |
| collection | DOAJ |
| description | BackgroundLow back pain and lower extremity sensory and functional abnormalities are common symptoms of lumbar disc herniation (LDH), which can easily cause walking dysfunction and significantly impair the quality of life of patients. Tuina and traditional Chinese exercises (TCEs) are effective in relieving pain and restoring dysfunction, and both are often used in China as a combination of passive therapy and active exercise to ease symptoms in patients with LDH. However, the majority of current clinical trials on the treatment of LDH with Tuina or TCEs are single-centre clinical studies, and the quality of these studies is generally low. Furthermore, clear evidence of clinical efficacy as to whether Tuina combined with TCEs is superior to single TCEs for improving dysfunction and pain in patients with LDH is lacking.Methods/designThe design is a multicentre, assessor-blinded clinical randomised controlled trial. A total of 166 patients with LDH (aged 18–65 years) were recruited from four centres and randomly assigned at a 1:1 ratio to two groups: the TCE group and the Tuina combined with the TCE group. Each group received three treatments over the course of 1 week for a total of 4 weeks. The primary outcome indicator was the Oswestry Disability Index, whereas the secondary outcome indicators were the Short Form of Quality of Life Scale, the Short-Form McGill Pain Questionnaire Scale, and gait analysis. Assessments were made before the treatment, at the end of the treatment, and at the third and sixth months’ follow-ups. Gait analysis was only used for comparison between the two groups before and after treatment, and did not involve follow-up. Adverse events occurring during the trial were faithfully recorded.ConclusionThe results of this study are expected to provide a more effective research protocol for symptomatic LDH and an evidence-based rationale for the efficacy and safety of Tuina combined with TCEs in the treatment of symptomatic LDH.Clinical trial registrationhttps://www.chictr.org.cn/showproj.html?proj=209956, identifier ChiCTR2300077361. |
| format | Article |
| id | doaj-art-dcfc198cf2e14e8791aca794f3e67ad9 |
| institution | Kabale University |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-dcfc198cf2e14e8791aca794f3e67ad92025-01-24T05:21:24ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-01-011610.3389/fneur.2025.14979331497933Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocolZhihong Fan0Shenghong Jia1Xin Zhou2Chao Li3Jiahao Shao4Xiaofeng Liu5Yitao Liao6Yenan Xu7Dandan He8Shixiang Wu9Xian Zhang10Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaDepartment of Spine, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaYueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaDepartment of Spine, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaDepartment of Spine, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaWuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaDepartment of Spine, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, ChinaBackgroundLow back pain and lower extremity sensory and functional abnormalities are common symptoms of lumbar disc herniation (LDH), which can easily cause walking dysfunction and significantly impair the quality of life of patients. Tuina and traditional Chinese exercises (TCEs) are effective in relieving pain and restoring dysfunction, and both are often used in China as a combination of passive therapy and active exercise to ease symptoms in patients with LDH. However, the majority of current clinical trials on the treatment of LDH with Tuina or TCEs are single-centre clinical studies, and the quality of these studies is generally low. Furthermore, clear evidence of clinical efficacy as to whether Tuina combined with TCEs is superior to single TCEs for improving dysfunction and pain in patients with LDH is lacking.Methods/designThe design is a multicentre, assessor-blinded clinical randomised controlled trial. A total of 166 patients with LDH (aged 18–65 years) were recruited from four centres and randomly assigned at a 1:1 ratio to two groups: the TCE group and the Tuina combined with the TCE group. Each group received three treatments over the course of 1 week for a total of 4 weeks. The primary outcome indicator was the Oswestry Disability Index, whereas the secondary outcome indicators were the Short Form of Quality of Life Scale, the Short-Form McGill Pain Questionnaire Scale, and gait analysis. Assessments were made before the treatment, at the end of the treatment, and at the third and sixth months’ follow-ups. Gait analysis was only used for comparison between the two groups before and after treatment, and did not involve follow-up. Adverse events occurring during the trial were faithfully recorded.ConclusionThe results of this study are expected to provide a more effective research protocol for symptomatic LDH and an evidence-based rationale for the efficacy and safety of Tuina combined with TCEs in the treatment of symptomatic LDH.Clinical trial registrationhttps://www.chictr.org.cn/showproj.html?proj=209956, identifier ChiCTR2300077361.https://www.frontiersin.org/articles/10.3389/fneur.2025.1497933/fulllumbar disc herniationTuina therapytraditional Chinese exercisesrandomised controlled trialstudy protocol |
| spellingShingle | Zhihong Fan Shenghong Jia Xin Zhou Chao Li Jiahao Shao Xiaofeng Liu Yitao Liao Yenan Xu Dandan He Shixiang Wu Xian Zhang Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol Frontiers in Neurology lumbar disc herniation Tuina therapy traditional Chinese exercises randomised controlled trial study protocol |
| title | Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol |
| title_full | Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol |
| title_fullStr | Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol |
| title_full_unstemmed | Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol |
| title_short | Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol |
| title_sort | clinical efficacy of tuina therapy combined with traditional chinese exercises in the treatment of symptomatic lumbar disc herniation a multicentre randomised controlled trial protocol |
| topic | lumbar disc herniation Tuina therapy traditional Chinese exercises randomised controlled trial study protocol |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2025.1497933/full |
| work_keys_str_mv | AT zhihongfan clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT shenghongjia clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT xinzhou clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT chaoli clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT jiahaoshao clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT xiaofengliu clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT yitaoliao clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT yenanxu clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT dandanhe clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT shixiangwu clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol AT xianzhang clinicalefficacyoftuinatherapycombinedwithtraditionalchineseexercisesinthetreatmentofsymptomaticlumbardischerniationamulticentrerandomisedcontrolledtrialprotocol |