Development and Validation of HPLC-MS/MS Method for Busereline Quantitation in Animal Blood Plasma

Development and Validation of HPLC-MS/MS Method for Busereline Quantitation in Animal Blood Plasma

Introduction. Busereline, being a synthetic gonadotropin-releasing hormone analog, is widely used for hormone-dependent cancer treatment (e.g. prostate cancer and breast cancer). Based on the accumulated scientific data for busereline quantitation in biosamples, the main analytical method that is us...

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Bibliographic Details
Main Authors: E. N. Fisher, E. S. Melnikov, I. Е. Shohin
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-09-01
Series:Разработка и регистрация лекарственных средств
Subjects:
peptides
busereline
pharmacokinetics
hpls-ms/ms
gonadotropin-releasing hormone analogs
validation
Online Access:https://www.pharmjournal.ru/jour/article/view/718
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