m6A-modified CTC-297N7.9 inhibits hepatocellular carcinoma metastasis via epigenetically downregulating CCL2 and CD47

m6A-modified CTC-297N7.9 inhibits hepatocellular carcinoma metastasis via epigenetically downregulating CCL2 and CD47

Abstract Background Hepatocellular carcinoma (HCC) is one of most common malignancies with poor prognosis, largely due to its high propensity for metastasis and recurrence. As the most common internal RNA modification, N6-methyladenosine (m6A) plays critical and diverse roles in HCC progression. How...

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Bibliographic Details
Main Authors: Huamei Wei, Changhong Pu, Min Zeng, Rongzhou Lu, Yunyu Wei, Yanyan Huang, Zheng Huang, Lizheng Huang, Zuoming Xu, Jianchu Wang, Rihai Ma, Jian Pu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cancer Cell International
Subjects:
N6-methyladenosine
Hepatocellular carcinoma
Metastasis
Macrophage
Phagocytosis
Epigenetic modulation
Online Access:https://doi.org/10.1186/s12935-025-03857-0
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