Control of a Clonal Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Hospital of the Basque Country after the Introduction of Environmental Cleaning Led by the Systematic Sampling from Environmental Objects
Background. Between July 2009 and September 2010, an outbreak of multidrug-resistant (MDR) Acinetobacter baumannii was detected in one critical care unit of a tertiary hospital in the Basque Country, involving 49 infected and 16 colonized patients. The aim was to evaluate the impact of environmental...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Interdisciplinary Perspectives on Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2013/582831 |
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| author | Jesús Delgado Naranjo José Ignacio Villate Navarro Mercedes Sota Busselo Alberto Martínez Ruíz José María Hernández Hernández María Pilar Torres Garmendia María Isabel Urcelay López |
| author_facet | Jesús Delgado Naranjo José Ignacio Villate Navarro Mercedes Sota Busselo Alberto Martínez Ruíz José María Hernández Hernández María Pilar Torres Garmendia María Isabel Urcelay López |
| author_sort | Jesús Delgado Naranjo |
| collection | DOAJ |
| description | Background. Between July 2009 and September 2010, an outbreak of multidrug-resistant (MDR) Acinetobacter baumannii was detected in one critical care unit of a tertiary hospital in the Basque Country, involving 49 infected and 16 colonized patients. The aim was to evaluate the impact of environmental cleaning and systematic sampling from environmental objects on the risk of infection by MDR A. baumannii. Methods. After systematic sampling from environmental objects and molecular typing of all new MDR A. baumannii strains from patients and environmental isolates, we analyzed the correlation (Pearson’s r) between new infected cases and positive environmental samples. The risk ratio (RR) of infection was estimated with Poisson regression. Results. The risk increased significantly with the number of positive samples in common areas (RR = 1.40; 95%CI = 0.99–1.94) and positive samples in boxes (RR = 1.19; 95%CI = 1.01–1.40). The number of cases also positively correlated with positive samples in boxes (r=0.50; P<0.05) and common areas (r=0.29; P=0.18). Conclusion. Once conventional measures have failed, environmental cleaning, guided by systematic sampling from environmental objects, provided the objective risk reduction of new cases and enabled the full control of the outbreak. |
| format | Article |
| id | doaj-art-dc8edc75149046e1b8070331f3fb5734 |
| institution | Kabale University |
| issn | 1687-708X 1687-7098 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Interdisciplinary Perspectives on Infectious Diseases |
| spelling | doaj-art-dc8edc75149046e1b8070331f3fb57342025-02-03T01:09:40ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982013-01-01201310.1155/2013/582831582831Control of a Clonal Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Hospital of the Basque Country after the Introduction of Environmental Cleaning Led by the Systematic Sampling from Environmental ObjectsJesús Delgado Naranjo0José Ignacio Villate Navarro1Mercedes Sota Busselo2Alberto Martínez Ruíz3José María Hernández Hernández4María Pilar Torres Garmendia5María Isabel Urcelay López6Service of Preventive Medicine, University Hospital of Cruces, Basque Health Service OSAKIDETZA, 48903 Barakaldo, Bizkaia, SpainService of Preventive Medicine, University Hospital of Cruces, Basque Health Service OSAKIDETZA, 48903 Barakaldo, Bizkaia, SpainLaboratory of Microbiology, University Hospital of Cruces, Basque Health Service OSAKIDETZA, 48903 Barakaldo, Bizkaia, SpainService of Anaesthesia and Reanimation, University Hospital of Cruces, Basque Health Service OSAKIDETZA, 48903 Barakaldo, Bizkaia, SpainService of Preventive Medicine, University Hospital of Cruces, Basque Health Service OSAKIDETZA, 48903 Barakaldo, Bizkaia, SpainService of Anaesthesia and Reanimation, University Hospital of Cruces, Basque Health Service OSAKIDETZA, 48903 Barakaldo, Bizkaia, SpainService of Preventive Medicine, University Hospital of Cruces, Basque Health Service OSAKIDETZA, 48903 Barakaldo, Bizkaia, SpainBackground. Between July 2009 and September 2010, an outbreak of multidrug-resistant (MDR) Acinetobacter baumannii was detected in one critical care unit of a tertiary hospital in the Basque Country, involving 49 infected and 16 colonized patients. The aim was to evaluate the impact of environmental cleaning and systematic sampling from environmental objects on the risk of infection by MDR A. baumannii. Methods. After systematic sampling from environmental objects and molecular typing of all new MDR A. baumannii strains from patients and environmental isolates, we analyzed the correlation (Pearson’s r) between new infected cases and positive environmental samples. The risk ratio (RR) of infection was estimated with Poisson regression. Results. The risk increased significantly with the number of positive samples in common areas (RR = 1.40; 95%CI = 0.99–1.94) and positive samples in boxes (RR = 1.19; 95%CI = 1.01–1.40). The number of cases also positively correlated with positive samples in boxes (r=0.50; P<0.05) and common areas (r=0.29; P=0.18). Conclusion. Once conventional measures have failed, environmental cleaning, guided by systematic sampling from environmental objects, provided the objective risk reduction of new cases and enabled the full control of the outbreak.http://dx.doi.org/10.1155/2013/582831 |
| spellingShingle | Jesús Delgado Naranjo José Ignacio Villate Navarro Mercedes Sota Busselo Alberto Martínez Ruíz José María Hernández Hernández María Pilar Torres Garmendia María Isabel Urcelay López Control of a Clonal Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Hospital of the Basque Country after the Introduction of Environmental Cleaning Led by the Systematic Sampling from Environmental Objects Interdisciplinary Perspectives on Infectious Diseases |
| title | Control of a Clonal Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Hospital of the Basque Country after the Introduction of Environmental Cleaning Led by the Systematic Sampling from Environmental Objects |
| title_full | Control of a Clonal Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Hospital of the Basque Country after the Introduction of Environmental Cleaning Led by the Systematic Sampling from Environmental Objects |
| title_fullStr | Control of a Clonal Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Hospital of the Basque Country after the Introduction of Environmental Cleaning Led by the Systematic Sampling from Environmental Objects |
| title_full_unstemmed | Control of a Clonal Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Hospital of the Basque Country after the Introduction of Environmental Cleaning Led by the Systematic Sampling from Environmental Objects |
| title_short | Control of a Clonal Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Hospital of the Basque Country after the Introduction of Environmental Cleaning Led by the Systematic Sampling from Environmental Objects |
| title_sort | control of a clonal outbreak of multidrug resistant acinetobacter baumannii in a hospital of the basque country after the introduction of environmental cleaning led by the systematic sampling from environmental objects |
| url | http://dx.doi.org/10.1155/2013/582831 |
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