Investigating intra‐tumoural heterogeneity and microenvironment diversity in primary cardiac angiosarcoma through single‐cell RNA sequencing

Investigating intra‐tumoural heterogeneity and microenvironment diversity in primary cardiac angiosarcoma through single‐cell RNA sequencing

Abstract Background Primary cardiac angiosarcoma (PCAS) is a rare and aggressive heart tumour with limited treatment options and a poor prognosis. Understanding cellular heterogeneity and tumour microenvironment (TME) is crucial for the development of effective therapies. Here, we investigated the i...

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Main Authors: Jingyuan Huo, Zhen Wang, Wenting Zhao, Miao Chen, Haoyang Li, Fengpu He, Xiao Tian, Yaqi Ma, Firyuza Husanova, Liang Ma, Yiming Ni, Hongda Ding, Weidong Li, Hongfei Xu
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Clinical and Translational Medicine
Subjects:
heterogeneity
multicolour immunohistochemistry
primary cardiac angiosarcoma
single‐cell RNA sequencing
tumour microenvironment
Online Access:https://doi.org/10.1002/ctm2.70113
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