Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells

Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells

BackgroundAdjuvant-induced arthritis (AIA) serves as a classic model for rheumatoid arthritis (RA), typified by inflammatory cell infiltration and joint damage. This study explores the therapeutic efficacy of HU-308, a CB2 receptor-specific agonist, on inflammation and immune balance in AIA.MethodsA...

Full description

Saved in:
Bibliographic Details
Main Authors: Na Tian, Cui Yang, Yu Du, Miao Chen, Bin Li, Dan Li, Sheng-Ming Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
cannabinoid receptor 2
Th17/Treg balance
adjuvant-induced arthritis
cd4+ T cell differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1532518/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items