Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light Spectroscopy

Clinical trials have reported statistically significant and clinically relevant effects of homeopathic preparations. We applied ultraviolet (UV) spectroscopy to investigate the physical properties of homeopathic preparations and to contribute to an understanding of the not-yet-identified mode of act...

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Main Authors: Barbara Marschollek, Mathias Nelle, Martin Wolf, Stephan Baumgartner, Peter Heusser, Ursula Wolf
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2010.15
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author Barbara Marschollek
Mathias Nelle
Martin Wolf
Stephan Baumgartner
Peter Heusser
Ursula Wolf
author_facet Barbara Marschollek
Mathias Nelle
Martin Wolf
Stephan Baumgartner
Peter Heusser
Ursula Wolf
author_sort Barbara Marschollek
collection DOAJ
description Clinical trials have reported statistically significant and clinically relevant effects of homeopathic preparations. We applied ultraviolet (UV) spectroscopy to investigate the physical properties of homeopathic preparations and to contribute to an understanding of the not-yet-identified mode of action. In previous investigations, homeopathic preparations had significantly lower UV light transmissions than controls. The aim of this study was to explore the possible effects of external factors (UV light and temperature) on the homeopathic preparations. Homeopathic centesimal (c) dilutions, 1c to 30c, of copper sulfate (CuSO4), decimal dilutions of sulfur (S8), 1x to 30x, and controls (succussed potentization medium) were prepared, randomized, and blinded. UV transmission was measured at six different time points after preparation (from 4 to 256 days). In addition, one series of samples was exposed to UV light of a sterilization lamp for 12 h, one was incubated at 37°C for 24 h, and one was heated to 90°C for 15 min. UV light transmission values from 190 or 220 nm to 340 nm were measured several times and averaged. After each exposure, UV transmission of the homeopathic preparations of CuSO4 was significantly reduced compared to the controls, particularly after heating to 37°C. Overall, the nonexposed CuSO4 preparations did not show significantly lower UV transmission compared to controls; however, the pooled subgroup of measurements at days 26, 33, and 110 yielded significant differences. UV light transmission for S8 preparations did not show any differences compared to controls. Our conclusion is that exposure to external factors, incubation at 37°C in particular, increases the difference in light transmission of homeopathic CuSO4 preparations compared to controls.
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spelling doaj-art-dc69f76bc2ba4fd295f5e28ff0f2adb02025-02-03T05:48:17ZengWileyThe Scientific World Journal1537-744X2010-01-0110496110.1100/tsw.2010.15Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light SpectroscopyBarbara Marschollek0Mathias Nelle1Martin Wolf2Stephan Baumgartner3Peter Heusser4Ursula Wolf5Institute of Complementary Medicine KIKOM, University of Bern, SwitzerlandDivision of Neonatology, University Hospital Bern, SwitzerlandInstitute of Complementary Medicine KIKOM, University of Bern, SwitzerlandInstitute of Complementary Medicine KIKOM, University of Bern, SwitzerlandInstitute of Complementary Medicine KIKOM, University of Bern, SwitzerlandInstitute of Complementary Medicine KIKOM, University of Bern, SwitzerlandClinical trials have reported statistically significant and clinically relevant effects of homeopathic preparations. We applied ultraviolet (UV) spectroscopy to investigate the physical properties of homeopathic preparations and to contribute to an understanding of the not-yet-identified mode of action. In previous investigations, homeopathic preparations had significantly lower UV light transmissions than controls. The aim of this study was to explore the possible effects of external factors (UV light and temperature) on the homeopathic preparations. Homeopathic centesimal (c) dilutions, 1c to 30c, of copper sulfate (CuSO4), decimal dilutions of sulfur (S8), 1x to 30x, and controls (succussed potentization medium) were prepared, randomized, and blinded. UV transmission was measured at six different time points after preparation (from 4 to 256 days). In addition, one series of samples was exposed to UV light of a sterilization lamp for 12 h, one was incubated at 37°C for 24 h, and one was heated to 90°C for 15 min. UV light transmission values from 190 or 220 nm to 340 nm were measured several times and averaged. After each exposure, UV transmission of the homeopathic preparations of CuSO4 was significantly reduced compared to the controls, particularly after heating to 37°C. Overall, the nonexposed CuSO4 preparations did not show significantly lower UV transmission compared to controls; however, the pooled subgroup of measurements at days 26, 33, and 110 yielded significant differences. UV light transmission for S8 preparations did not show any differences compared to controls. Our conclusion is that exposure to external factors, incubation at 37°C in particular, increases the difference in light transmission of homeopathic CuSO4 preparations compared to controls.http://dx.doi.org/10.1100/tsw.2010.15
spellingShingle Barbara Marschollek
Mathias Nelle
Martin Wolf
Stephan Baumgartner
Peter Heusser
Ursula Wolf
Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light Spectroscopy
The Scientific World Journal
title Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light Spectroscopy
title_full Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light Spectroscopy
title_fullStr Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light Spectroscopy
title_full_unstemmed Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light Spectroscopy
title_short Effects of Exposure to Physical Factors on Homeopathic Preparations as Determined by Ultraviolet Light Spectroscopy
title_sort effects of exposure to physical factors on homeopathic preparations as determined by ultraviolet light spectroscopy
url http://dx.doi.org/10.1100/tsw.2010.15
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