Interorgan Crosstalk Contributing to β-Cell Dysfunction
Type 2 diabetes mellitus (T2DM) results from pancreatic β-cell failure in the setting of insulin resistance. In the early stages of this disease, pancreatic β-cells meet increased insulin demand by both enhancing insulin-secretory capacity and increasing β-cell mass. As the disease progresses, β-cel...
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Main Authors: | Katsuya Tanabe, Kikuko Amo-Shiinoki, Masayuki Hatanaka, Yukio Tanizawa |
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Format: | Article |
Language: | English |
Published: |
Wiley
2017-01-01
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Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2017/3605178 |
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