In-depth proteomic profiling identifies potentiation of the LPS response by 7-ketocholesterol

In-depth proteomic profiling identifies potentiation of the LPS response by 7-ketocholesterol

In patients with stable coronary artery disease, plasma levels of 7-ketocholesterol (7-KC), found at high levels in atherosclerotic lesions, predict risk of incident heart failure dose dependently, potentially contributing to disease aetiology. Previous studies demonstrated that 7-KC can elicit effe...

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Bibliographic Details
Main Authors:	Iain R. Phair, Magdalena Sovakova, Noor Alqurashi, Raid B. Nisr, Alison D. McNeilly, Douglas Lamont, Graham Rena
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Series:	Journal of Molecular and Cellular Cardiology Plus
Subjects:	Ketocholesterol Oxysterol Macrophages Cholesterol Inflammation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2772976125000042
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