Type II Acute Macular Neuroretinopathy Secondary to Malaria

To the best of our knowledge, we present the first case of type II acute macular neuroretinopathy (AMN) exhibiting in a patient suffering from malarial retinopathy concomitant with cerebral malaria acquired after travelling to West Africa without taking the necessary antimalarial prophylaxis. The pa...

Full description

Saved in:
Bibliographic Details
Main Authors: Alastair David Bezzina, Jeremy Spiteri Bailey, Isaac Bertuello
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2024/1577127
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832546227823050752
author Alastair David Bezzina
Jeremy Spiteri Bailey
Isaac Bertuello
author_facet Alastair David Bezzina
Jeremy Spiteri Bailey
Isaac Bertuello
author_sort Alastair David Bezzina
collection DOAJ
description To the best of our knowledge, we present the first case of type II acute macular neuroretinopathy (AMN) exhibiting in a patient suffering from malarial retinopathy concomitant with cerebral malaria acquired after travelling to West Africa without taking the necessary antimalarial prophylaxis. The patient complained of bilateral blurring of vision after being removed off sedation whilst at the intensive care unit. Subsequent examination revealed bilateral retinal haemorrhages, cotton-wool spots, and foveal pigmentary changes in keeping malarial retinopathy. Macular optical coherence tomography (OCT) revealed patchy hyperreflective changes at the level of the outer plexiform and outer nuclear layers (ONL) in keeping with the areas of deep capillary plexus flow void noted on OCT-angiography (OCT-A). This case report sheds more light on the extent of neurosensory retinal ischaemia in malarial retinopathy and showcases a new imaging biomarker which may be utilized in assessing and quantifying the functional deficit created by this disease.
format Article
id doaj-art-dc4d9c3511fe4e72a00994ee3af521a5
institution Kabale University
issn 2090-6730
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series Case Reports in Ophthalmological Medicine
spelling doaj-art-dc4d9c3511fe4e72a00994ee3af521a52025-02-03T07:23:38ZengWileyCase Reports in Ophthalmological Medicine2090-67302024-01-01202410.1155/2024/1577127Type II Acute Macular Neuroretinopathy Secondary to MalariaAlastair David Bezzina0Jeremy Spiteri Bailey1Isaac Bertuello2Ophthalmology DepartmentOphthalmology DepartmentOphthalmology DepartmentTo the best of our knowledge, we present the first case of type II acute macular neuroretinopathy (AMN) exhibiting in a patient suffering from malarial retinopathy concomitant with cerebral malaria acquired after travelling to West Africa without taking the necessary antimalarial prophylaxis. The patient complained of bilateral blurring of vision after being removed off sedation whilst at the intensive care unit. Subsequent examination revealed bilateral retinal haemorrhages, cotton-wool spots, and foveal pigmentary changes in keeping malarial retinopathy. Macular optical coherence tomography (OCT) revealed patchy hyperreflective changes at the level of the outer plexiform and outer nuclear layers (ONL) in keeping with the areas of deep capillary plexus flow void noted on OCT-angiography (OCT-A). This case report sheds more light on the extent of neurosensory retinal ischaemia in malarial retinopathy and showcases a new imaging biomarker which may be utilized in assessing and quantifying the functional deficit created by this disease.http://dx.doi.org/10.1155/2024/1577127
spellingShingle Alastair David Bezzina
Jeremy Spiteri Bailey
Isaac Bertuello
Type II Acute Macular Neuroretinopathy Secondary to Malaria
Case Reports in Ophthalmological Medicine
title Type II Acute Macular Neuroretinopathy Secondary to Malaria
title_full Type II Acute Macular Neuroretinopathy Secondary to Malaria
title_fullStr Type II Acute Macular Neuroretinopathy Secondary to Malaria
title_full_unstemmed Type II Acute Macular Neuroretinopathy Secondary to Malaria
title_short Type II Acute Macular Neuroretinopathy Secondary to Malaria
title_sort type ii acute macular neuroretinopathy secondary to malaria
url http://dx.doi.org/10.1155/2024/1577127
work_keys_str_mv AT alastairdavidbezzina typeiiacutemacularneuroretinopathysecondarytomalaria
AT jeremyspiteribailey typeiiacutemacularneuroretinopathysecondarytomalaria
AT isaacbertuello typeiiacutemacularneuroretinopathysecondarytomalaria