Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats

Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats

Scopolamine, as a tropane alkaloid found in plants such as belladonna and datura, is used clinically as a transdermal patch and is highly neurotoxic. This study aimed to develop a simple, sensitive, and selective LC-MS/MS method for the determination of the content and distribution of scopolamine in...

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Bibliographic Details
Main Authors:	Juan Chen, Anjing Lu, Daopeng Tan, Qianru Zhang, Yanliu Lu, Lin Qin, Yuqi He
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	International Journal of Analytical Chemistry
Online Access:	http://dx.doi.org/10.1155/2022/8536235
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