Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog
A 7-year-old male, Border Collie, developed a firm mass, measuring approximately 1 cm in diameter, in the left buccal skin. Histologically, the mass was composed of ductal structures lined by bilayered luminal epithelial and basaloid tumor cells along with a few nests of sebaceous cells. Immunohisto...
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Format: | Article |
Language: | English |
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Wiley
2013-01-01
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Series: | Case Reports in Veterinary Medicine |
Online Access: | http://dx.doi.org/10.1155/2013/167923 |
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author | Masaki Michishita Junki Yasui Rei Nakahira Hisashi Yoshimura Kimimasa Takahashi |
author_facet | Masaki Michishita Junki Yasui Rei Nakahira Hisashi Yoshimura Kimimasa Takahashi |
author_sort | Masaki Michishita |
collection | DOAJ |
description | A 7-year-old male, Border Collie, developed a firm mass, measuring approximately 1 cm in diameter, in the left buccal skin. Histologically, the mass was composed of ductal structures lined by bilayered luminal epithelial and basaloid tumor cells along with a few nests of sebaceous cells. Immunohistochemical staining revealed that the luminal epithelial tumor cells were positive for cytokeratin (CK, CAM5.2) and CK19 but not for CK14 or p63. In contrast, the basaloid tumor cells were positive for CK14, p63, and αSMA but not for CK19 or CAM5.2. CK8 expression was observed in both luminal epithelial and basaloid tumor cells. The tumor cells with sebaceous differentiation were positive for CK14 but not for the other markers. This is the first case of an apocrine sweat gland ductal adenoma with sebaceous differentiation occurring in the buccal skin of a dog. |
format | Article |
id | doaj-art-dc46528692154111921d314370ebede5 |
institution | Kabale University |
issn | 2090-7001 2090-701X |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Veterinary Medicine |
spelling | doaj-art-dc46528692154111921d314370ebede52025-02-03T06:10:54ZengWileyCase Reports in Veterinary Medicine2090-70012090-701X2013-01-01201310.1155/2013/167923167923Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a DogMasaki Michishita0Junki Yasui1Rei Nakahira2Hisashi Yoshimura3Kimimasa Takahashi4Department of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanDepartment of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanDepartment of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanDepartment of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanDepartment of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanA 7-year-old male, Border Collie, developed a firm mass, measuring approximately 1 cm in diameter, in the left buccal skin. Histologically, the mass was composed of ductal structures lined by bilayered luminal epithelial and basaloid tumor cells along with a few nests of sebaceous cells. Immunohistochemical staining revealed that the luminal epithelial tumor cells were positive for cytokeratin (CK, CAM5.2) and CK19 but not for CK14 or p63. In contrast, the basaloid tumor cells were positive for CK14, p63, and αSMA but not for CK19 or CAM5.2. CK8 expression was observed in both luminal epithelial and basaloid tumor cells. The tumor cells with sebaceous differentiation were positive for CK14 but not for the other markers. This is the first case of an apocrine sweat gland ductal adenoma with sebaceous differentiation occurring in the buccal skin of a dog.http://dx.doi.org/10.1155/2013/167923 |
spellingShingle | Masaki Michishita Junki Yasui Rei Nakahira Hisashi Yoshimura Kimimasa Takahashi Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog Case Reports in Veterinary Medicine |
title | Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog |
title_full | Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog |
title_fullStr | Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog |
title_full_unstemmed | Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog |
title_short | Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog |
title_sort | apocrine sweat gland ductal adenoma with sebaceous differentiation in a dog |
url | http://dx.doi.org/10.1155/2013/167923 |
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