Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog

A 7-year-old male, Border Collie, developed a firm mass, measuring approximately 1 cm in diameter, in the left buccal skin. Histologically, the mass was composed of ductal structures lined by bilayered luminal epithelial and basaloid tumor cells along with a few nests of sebaceous cells. Immunohisto...

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Main Authors: Masaki Michishita, Junki Yasui, Rei Nakahira, Hisashi Yoshimura, Kimimasa Takahashi
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Veterinary Medicine
Online Access:http://dx.doi.org/10.1155/2013/167923
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author Masaki Michishita
Junki Yasui
Rei Nakahira
Hisashi Yoshimura
Kimimasa Takahashi
author_facet Masaki Michishita
Junki Yasui
Rei Nakahira
Hisashi Yoshimura
Kimimasa Takahashi
author_sort Masaki Michishita
collection DOAJ
description A 7-year-old male, Border Collie, developed a firm mass, measuring approximately 1 cm in diameter, in the left buccal skin. Histologically, the mass was composed of ductal structures lined by bilayered luminal epithelial and basaloid tumor cells along with a few nests of sebaceous cells. Immunohistochemical staining revealed that the luminal epithelial tumor cells were positive for cytokeratin (CK, CAM5.2) and CK19 but not for CK14 or p63. In contrast, the basaloid tumor cells were positive for CK14, p63, and αSMA but not for CK19 or CAM5.2. CK8 expression was observed in both luminal epithelial and basaloid tumor cells. The tumor cells with sebaceous differentiation were positive for CK14 but not for the other markers. This is the first case of an apocrine sweat gland ductal adenoma with sebaceous differentiation occurring in the buccal skin of a dog.
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publishDate 2013-01-01
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series Case Reports in Veterinary Medicine
spelling doaj-art-dc46528692154111921d314370ebede52025-02-03T06:10:54ZengWileyCase Reports in Veterinary Medicine2090-70012090-701X2013-01-01201310.1155/2013/167923167923Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a DogMasaki Michishita0Junki Yasui1Rei Nakahira2Hisashi Yoshimura3Kimimasa Takahashi4Department of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanDepartment of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanDepartment of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanDepartment of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanDepartment of Veterinary Pathology, Nippon Veterinary and Life Science University, 1-7-1 Musashino, Kyounan-cho, Tokyo 180-8602, JapanA 7-year-old male, Border Collie, developed a firm mass, measuring approximately 1 cm in diameter, in the left buccal skin. Histologically, the mass was composed of ductal structures lined by bilayered luminal epithelial and basaloid tumor cells along with a few nests of sebaceous cells. Immunohistochemical staining revealed that the luminal epithelial tumor cells were positive for cytokeratin (CK, CAM5.2) and CK19 but not for CK14 or p63. In contrast, the basaloid tumor cells were positive for CK14, p63, and αSMA but not for CK19 or CAM5.2. CK8 expression was observed in both luminal epithelial and basaloid tumor cells. The tumor cells with sebaceous differentiation were positive for CK14 but not for the other markers. This is the first case of an apocrine sweat gland ductal adenoma with sebaceous differentiation occurring in the buccal skin of a dog.http://dx.doi.org/10.1155/2013/167923
spellingShingle Masaki Michishita
Junki Yasui
Rei Nakahira
Hisashi Yoshimura
Kimimasa Takahashi
Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog
Case Reports in Veterinary Medicine
title Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog
title_full Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog
title_fullStr Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog
title_full_unstemmed Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog
title_short Apocrine Sweat Gland Ductal Adenoma with Sebaceous Differentiation in a Dog
title_sort apocrine sweat gland ductal adenoma with sebaceous differentiation in a dog
url http://dx.doi.org/10.1155/2013/167923
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