Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue Diseases

Interstitial lung disease (ILD) associated with connective tissue diseases (CTDs) is highly heterogeneous in its clinical presentation and course. The diagnosis and management of CTD-ILD require a multidisciplinary approach involving, at minimum, a rheumatologist, a pulmonologist, and a radiologist....

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Main Authors: Matthew Koslow, Mehrnaz Maleki-Fischbach, Rebecca C. Keith
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2021/6677353
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author Matthew Koslow
Mehrnaz Maleki-Fischbach
Rebecca C. Keith
author_facet Matthew Koslow
Mehrnaz Maleki-Fischbach
Rebecca C. Keith
author_sort Matthew Koslow
collection DOAJ
description Interstitial lung disease (ILD) associated with connective tissue diseases (CTDs) is highly heterogeneous in its clinical presentation and course. The diagnosis and management of CTD-ILD require a multidisciplinary approach involving, at minimum, a rheumatologist, a pulmonologist, and a radiologist. Close monitoring of patients with CTD-ILD is important to enable early detection of disease progression and inform decisions regarding the initiation or escalation of pharmacotherapy. In the absence of guidelines regarding how CTD-ILDs should be treated, clinicians face difficult decisions on when to use immunosuppressant and anti-fibrotic therapies. The importance of a multidisciplinary and individualized approach to the diagnosis and management of CTD-ILD is highlighted in the three case studies that we describe in this article.
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spelling doaj-art-dc3ffed0467743c09751e68dec5888e82025-02-03T06:43:58ZengWileyCase Reports in Rheumatology2090-68892090-68972021-01-01202110.1155/2021/66773536677353Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue DiseasesMatthew Koslow0Mehrnaz Maleki-Fischbach1Rebecca C. Keith2Division of Pulmonary, Critical Care and Sleep Medicine, Interstitial Lung Disease Program, National Jewish Health, Denver, CO, USADivision of Rheumatology, National Jewish Health, Denver, CO, USADivision of Pulmonary, Critical Care and Sleep Medicine, Interstitial Lung Disease Program, National Jewish Health, Denver, CO, USAInterstitial lung disease (ILD) associated with connective tissue diseases (CTDs) is highly heterogeneous in its clinical presentation and course. The diagnosis and management of CTD-ILD require a multidisciplinary approach involving, at minimum, a rheumatologist, a pulmonologist, and a radiologist. Close monitoring of patients with CTD-ILD is important to enable early detection of disease progression and inform decisions regarding the initiation or escalation of pharmacotherapy. In the absence of guidelines regarding how CTD-ILDs should be treated, clinicians face difficult decisions on when to use immunosuppressant and anti-fibrotic therapies. The importance of a multidisciplinary and individualized approach to the diagnosis and management of CTD-ILD is highlighted in the three case studies that we describe in this article.http://dx.doi.org/10.1155/2021/6677353
spellingShingle Matthew Koslow
Mehrnaz Maleki-Fischbach
Rebecca C. Keith
Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue Diseases
Case Reports in Rheumatology
title Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue Diseases
title_full Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue Diseases
title_fullStr Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue Diseases
title_full_unstemmed Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue Diseases
title_short Diagnosis and Management of Interstitial Lung Disease in Patients with Connective Tissue Diseases
title_sort diagnosis and management of interstitial lung disease in patients with connective tissue diseases
url http://dx.doi.org/10.1155/2021/6677353
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