Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy
Immune-mediated necrotizing myopathy (IMNM) is a rare form of idiopathic immune myopathy (IIM) that requires immunotherapies, including immunosuppressive medications, if severe. There is a paucity of data regarding outcomes of patients with immune-mediated polymyositis who continue immunosuppressive...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2020/8886324 |
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| author | Thomas C. Bolig Nada Abdulaziz Elena Schiopu |
| author_facet | Thomas C. Bolig Nada Abdulaziz Elena Schiopu |
| author_sort | Thomas C. Bolig |
| collection | DOAJ |
| description | Immune-mediated necrotizing myopathy (IMNM) is a rare form of idiopathic immune myopathy (IIM) that requires immunotherapies, including immunosuppressive medications, if severe. There is a paucity of data regarding outcomes of patients with immune-mediated polymyositis who continue immunosuppressive medications during the COVID-19 pandemic. This is the first reported case of COVID-19 in a patient with IMNM. Despite being on two immunotherapies, having risk factors, and having radiographic abnormalities on chest X-ray, the patient had an unremarkable COVID-19 course. He was discharged from the emergency department with a 7-day course of azithromycin and quickly resumed his immunotherapies, but he experienced a flare in his myositis. The 14-week follow-up computed tomography (CT) was negative for residual pneumonitis or fibrosis. More data are needed regarding management and prognosis of patients with connective tissue diseases who become infected with SARS-CoV-2. |
| format | Article |
| id | doaj-art-dc301f1c70ac4f4f8bb82ce03c08e71e |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-dc301f1c70ac4f4f8bb82ce03c08e71e2025-02-03T01:05:15ZengWileyCase Reports in Rheumatology2090-68892090-68972020-01-01202010.1155/2020/88863248886324Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing MyopathyThomas C. Bolig0Nada Abdulaziz1Elena Schiopu2Department of Internal Medicine, University of Michigan, 1500 E Medical Ctr Dr, Ann Arbor, MI 48109, USADepartment of Rheumatology, University of Michigan, 1500 E Medical Ctr Dr, Ann Arbor, MI 48109, USADepartment of Internal Medicine, University of Michigan, 1500 E Medical Ctr Dr, Ann Arbor, MI 48109, USAImmune-mediated necrotizing myopathy (IMNM) is a rare form of idiopathic immune myopathy (IIM) that requires immunotherapies, including immunosuppressive medications, if severe. There is a paucity of data regarding outcomes of patients with immune-mediated polymyositis who continue immunosuppressive medications during the COVID-19 pandemic. This is the first reported case of COVID-19 in a patient with IMNM. Despite being on two immunotherapies, having risk factors, and having radiographic abnormalities on chest X-ray, the patient had an unremarkable COVID-19 course. He was discharged from the emergency department with a 7-day course of azithromycin and quickly resumed his immunotherapies, but he experienced a flare in his myositis. The 14-week follow-up computed tomography (CT) was negative for residual pneumonitis or fibrosis. More data are needed regarding management and prognosis of patients with connective tissue diseases who become infected with SARS-CoV-2.http://dx.doi.org/10.1155/2020/8886324 |
| spellingShingle | Thomas C. Bolig Nada Abdulaziz Elena Schiopu Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy Case Reports in Rheumatology |
| title | Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy |
| title_full | Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy |
| title_fullStr | Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy |
| title_full_unstemmed | Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy |
| title_short | Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy |
| title_sort | complete recovery from covid 19 bilateral pneumonia in an immunosuppressed man with immune mediated necrotizing myopathy |
| url | http://dx.doi.org/10.1155/2020/8886324 |
| work_keys_str_mv | AT thomascbolig completerecoveryfromcovid19bilateralpneumoniainanimmunosuppressedmanwithimmunemediatednecrotizingmyopathy AT nadaabdulaziz completerecoveryfromcovid19bilateralpneumoniainanimmunosuppressedmanwithimmunemediatednecrotizingmyopathy AT elenaschiopu completerecoveryfromcovid19bilateralpneumoniainanimmunosuppressedmanwithimmunemediatednecrotizingmyopathy |