The immunogenicity and safety of an investigational meningococcal serogroups A, C, W-135 and Y tetanus toxoid conjugate vaccine (ACWY-TT) compared with a licensed meningococcal tetravalent polysaccharide vaccine<subtitle>A randomized, controlled non-inferiority study</subtitle>

The immunogenicity and safety of an investigational meningococcal serogroups A, C, W-135 and Y tetanus toxoid conjugate vaccine (ACWY-TT) compared with a licensed meningococcal tetravalent polysaccharide vaccine<subtitle>A randomized, controlled non-inferiority study</subtitle>

Immunogenicity and safety of ACWY-TT compared with licensed ACWY polysaccharide vaccine (MenPS) in healthy adults, and lot-to-lot consistency of three ACWY-TT lots were evaluated in a phase 3, open, controlled study. Adults aged 18–55 y were randomized to receive ACWY-TT (one of three lots) or MenPS...

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Bibliographic Details
Main Authors: Ghassan Dbaibo, Noel Macalalad, Mari Rose Aplasca-De Los Reyes, Efren Dimaano, Véronique Bianco, Yaela Baine, Jacqueline M. Miller
Format: Article
Language:English
Published: Taylor & Francis Group 2012-07-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
ACWY-TT vaccine
Neisseria meningitidis
adult
bactericidal activity
conjugate vaccine
immunogenicity
Online Access:https://www.tandfonline.com/doi/10.4161/hv.20211
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