Assessment of Green Extraction Techniques in the Utilization of Oak Tree (<i>Quercus robur</i>) and Mugwort (<i>Artemisia vulgaris</i>) Biomass for the Production of Bioactive Extracts
The aim of this study was to investigate the suitability of Pressurized Liquid Extraction (PLE) and Supercritical Fluid Extraction (SFE) for <i>Quercus robur</i> bark and <i>Artemisia vulgaris</i> extraction. PLE of <i>Q. robur</i> and <i>A. vulgaris</i&g...
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2025-01-01
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| author | David Villanueva-Bermejo Diego Martín Hernández Elvis Judith Hernández Susana Santoyo Tiziana Fornari |
| author_facet | David Villanueva-Bermejo Diego Martín Hernández Elvis Judith Hernández Susana Santoyo Tiziana Fornari |
| author_sort | David Villanueva-Bermejo |
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| description | The aim of this study was to investigate the suitability of Pressurized Liquid Extraction (PLE) and Supercritical Fluid Extraction (SFE) for <i>Quercus robur</i> bark and <i>Artemisia vulgaris</i> extraction. PLE of <i>Q. robur</i> and <i>A. vulgaris</i> were carried out at different temperatures with water, ethanol and several hydroalcoholic mixtures. SFE of <i>A. vulgaris</i> was performed at different pressures and ethanol concentrations. The anti-inflammatory activity of <i>Q. robur</i> extracts, the antibacterial activity of <i>A. vulgaris</i> extracts and the antioxidant activity of the extracts from both materials were determined. The highest phenolic compound content and antioxidant activity of <i>Q. robur</i> extracts were achieved with water at 100 °C (487.97 mg GAE/g and 3741 µg trolox/g). The highest values for <i>A. vulgaris</i> extracts were obtained with ethanol at 200 °C (149.16 mg/g and 437.13 µmol/g). The ethanolic extract at 150 °C from <i>A. vulgaris</i> had a noticeable anti-inflammatory activity (inhibition of TNF-α and IL-6 secretion near basal values and inhibition of IL-1β higher than 80% at 20 µg/mL). <i>A. vulgaris</i> extracts obtained by SFE exerted antibacterial activity against <i>E. coli</i> (IC<sub>50</sub> of 1388 µg/mL with neat SCCO<sub>2</sub> at 15 MPa) and <i>S. aureus</i> (1406 µg/mL using SCCO<sub>2</sub> with 10% ethanol). |
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| institution | Kabale University |
| issn | 2297-8739 |
| language | English |
| publishDate | 2025-01-01 |
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| spelling | doaj-art-dbf85211e36b434187fcfda838a6ffcb2025-01-24T13:49:33ZengMDPI AGSeparations2297-87392025-01-011211710.3390/separations12010017Assessment of Green Extraction Techniques in the Utilization of Oak Tree (<i>Quercus robur</i>) and Mugwort (<i>Artemisia vulgaris</i>) Biomass for the Production of Bioactive ExtractsDavid Villanueva-Bermejo0Diego Martín Hernández1Elvis Judith Hernández2Susana Santoyo3Tiziana Fornari4Institute of Food Science Research (CIAL CSIC-UAM). Departmental Section of Food Science, Faculty of Science, Autonomous University of Madrid (UAM), C/Nicolás Cabrera 9, 28049 Madrid, SpainInstitute of Food Science Research (CIAL CSIC-UAM). Departmental Section of Food Science, Faculty of Science, Autonomous University of Madrid (UAM), C/Nicolás Cabrera 9, 28049 Madrid, SpainInstitute of Food Science Research (CIAL CSIC-UAM). Departmental Section of Food Science, Faculty of Science, Autonomous University of Madrid (UAM), C/Nicolás Cabrera 9, 28049 Madrid, SpainInstitute of Food Science Research (CIAL CSIC-UAM). Departmental Section of Food Science, Faculty of Science, Autonomous University of Madrid (UAM), C/Nicolás Cabrera 9, 28049 Madrid, SpainInstitute of Food Science Research (CIAL CSIC-UAM). Departmental Section of Food Science, Faculty of Science, Autonomous University of Madrid (UAM), C/Nicolás Cabrera 9, 28049 Madrid, SpainThe aim of this study was to investigate the suitability of Pressurized Liquid Extraction (PLE) and Supercritical Fluid Extraction (SFE) for <i>Quercus robur</i> bark and <i>Artemisia vulgaris</i> extraction. PLE of <i>Q. robur</i> and <i>A. vulgaris</i> were carried out at different temperatures with water, ethanol and several hydroalcoholic mixtures. SFE of <i>A. vulgaris</i> was performed at different pressures and ethanol concentrations. The anti-inflammatory activity of <i>Q. robur</i> extracts, the antibacterial activity of <i>A. vulgaris</i> extracts and the antioxidant activity of the extracts from both materials were determined. The highest phenolic compound content and antioxidant activity of <i>Q. robur</i> extracts were achieved with water at 100 °C (487.97 mg GAE/g and 3741 µg trolox/g). The highest values for <i>A. vulgaris</i> extracts were obtained with ethanol at 200 °C (149.16 mg/g and 437.13 µmol/g). The ethanolic extract at 150 °C from <i>A. vulgaris</i> had a noticeable anti-inflammatory activity (inhibition of TNF-α and IL-6 secretion near basal values and inhibition of IL-1β higher than 80% at 20 µg/mL). <i>A. vulgaris</i> extracts obtained by SFE exerted antibacterial activity against <i>E. coli</i> (IC<sub>50</sub> of 1388 µg/mL with neat SCCO<sub>2</sub> at 15 MPa) and <i>S. aureus</i> (1406 µg/mL using SCCO<sub>2</sub> with 10% ethanol).https://www.mdpi.com/2297-8739/12/1/17antibacterialanti-inflammatoryantioxidant activity<i>Artemisia vulgaris</i>pressurize liquid extraction<i>Quercus robur</i> |
| spellingShingle | David Villanueva-Bermejo Diego Martín Hernández Elvis Judith Hernández Susana Santoyo Tiziana Fornari Assessment of Green Extraction Techniques in the Utilization of Oak Tree (<i>Quercus robur</i>) and Mugwort (<i>Artemisia vulgaris</i>) Biomass for the Production of Bioactive Extracts Separations antibacterial anti-inflammatory antioxidant activity <i>Artemisia vulgaris</i> pressurize liquid extraction <i>Quercus robur</i> |
| title | Assessment of Green Extraction Techniques in the Utilization of Oak Tree (<i>Quercus robur</i>) and Mugwort (<i>Artemisia vulgaris</i>) Biomass for the Production of Bioactive Extracts |
| title_full | Assessment of Green Extraction Techniques in the Utilization of Oak Tree (<i>Quercus robur</i>) and Mugwort (<i>Artemisia vulgaris</i>) Biomass for the Production of Bioactive Extracts |
| title_fullStr | Assessment of Green Extraction Techniques in the Utilization of Oak Tree (<i>Quercus robur</i>) and Mugwort (<i>Artemisia vulgaris</i>) Biomass for the Production of Bioactive Extracts |
| title_full_unstemmed | Assessment of Green Extraction Techniques in the Utilization of Oak Tree (<i>Quercus robur</i>) and Mugwort (<i>Artemisia vulgaris</i>) Biomass for the Production of Bioactive Extracts |
| title_short | Assessment of Green Extraction Techniques in the Utilization of Oak Tree (<i>Quercus robur</i>) and Mugwort (<i>Artemisia vulgaris</i>) Biomass for the Production of Bioactive Extracts |
| title_sort | assessment of green extraction techniques in the utilization of oak tree i quercus robur i and mugwort i artemisia vulgaris i biomass for the production of bioactive extracts |
| topic | antibacterial anti-inflammatory antioxidant activity <i>Artemisia vulgaris</i> pressurize liquid extraction <i>Quercus robur</i> |
| url | https://www.mdpi.com/2297-8739/12/1/17 |
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