Mixed Botryoid and Spindle Cell Bladder Rhabdomyosarcoma: An Outstanding Pediatric Case

We report a case of a 3-year-old North African child, initially assessed for nonspecific urinary symptoms such as haematuria and burning urination. The ultrasound evaluation showed a vegetating mass occupying the lumen with weak vascular signs at the Colour-Doppler evaluation. An explorative cystosc...

Full description

Saved in:
Bibliographic Details
Main Authors: Tommaso Alterio, Roberto Chimenz, Salvatore Arena, Giovanni Conti, Sabrina Cardile, Carmelo Romeo, Carmelo Salpietro, Carmelo Fede
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2017/8397826
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832566716170764288
author Tommaso Alterio
Roberto Chimenz
Salvatore Arena
Giovanni Conti
Sabrina Cardile
Carmelo Romeo
Carmelo Salpietro
Carmelo Fede
author_facet Tommaso Alterio
Roberto Chimenz
Salvatore Arena
Giovanni Conti
Sabrina Cardile
Carmelo Romeo
Carmelo Salpietro
Carmelo Fede
author_sort Tommaso Alterio
collection DOAJ
description We report a case of a 3-year-old North African child, initially assessed for nonspecific urinary symptoms such as haematuria and burning urination. The ultrasound evaluation showed a vegetating mass occupying the lumen with weak vascular signs at the Colour-Doppler evaluation. An explorative cystoscopy was performed and it revealed a nonbleeding lesion, white in colour, pedunculated, projecting into the lumen, and associated with a brown satellite formation. Histological examination showed a mixed Botryoid and Spindle Cell Rhabdomyosarcoma. This mixed histology has not been described before and no statistical data are reported in literature so far. Despite the Embryonal Rhabdomyosarcoma variant being the most common, the association characterized by two histological Rhabdomyosarcoma subtypes such as Botryoid and Spindle Cell is rarely observed and it is important to get an accurate histological diagnosis in order to immediately start the correct treatment protocol.
format Article
id doaj-art-dbf7944ddbbb42758601b8013bfcfe6f
institution Kabale University
issn 2090-6803
2090-6811
language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Pediatrics
spelling doaj-art-dbf7944ddbbb42758601b8013bfcfe6f2025-02-03T01:03:26ZengWileyCase Reports in Pediatrics2090-68032090-68112017-01-01201710.1155/2017/83978268397826Mixed Botryoid and Spindle Cell Bladder Rhabdomyosarcoma: An Outstanding Pediatric CaseTommaso Alterio0Roberto Chimenz1Salvatore Arena2Giovanni Conti3Sabrina Cardile4Carmelo Romeo5Carmelo Salpietro6Carmelo Fede7Department of Pediatric Sciences, University of Messina, Messina, ItalyDepartment of Pediatric Sciences, University of Messina, Messina, ItalyDepartment of Pediatric Surgery, University of Messina, Messina, ItalyDepartment of Pediatric Sciences, University of Messina, Messina, ItalyDepartment of Pediatric Sciences, University of Messina, Messina, ItalyDepartment of Pediatric Surgery, University of Messina, Messina, ItalyDepartment of Pediatric Sciences, University of Messina, Messina, ItalyDepartment of Pediatric Sciences, University of Messina, Messina, ItalyWe report a case of a 3-year-old North African child, initially assessed for nonspecific urinary symptoms such as haematuria and burning urination. The ultrasound evaluation showed a vegetating mass occupying the lumen with weak vascular signs at the Colour-Doppler evaluation. An explorative cystoscopy was performed and it revealed a nonbleeding lesion, white in colour, pedunculated, projecting into the lumen, and associated with a brown satellite formation. Histological examination showed a mixed Botryoid and Spindle Cell Rhabdomyosarcoma. This mixed histology has not been described before and no statistical data are reported in literature so far. Despite the Embryonal Rhabdomyosarcoma variant being the most common, the association characterized by two histological Rhabdomyosarcoma subtypes such as Botryoid and Spindle Cell is rarely observed and it is important to get an accurate histological diagnosis in order to immediately start the correct treatment protocol.http://dx.doi.org/10.1155/2017/8397826
spellingShingle Tommaso Alterio
Roberto Chimenz
Salvatore Arena
Giovanni Conti
Sabrina Cardile
Carmelo Romeo
Carmelo Salpietro
Carmelo Fede
Mixed Botryoid and Spindle Cell Bladder Rhabdomyosarcoma: An Outstanding Pediatric Case
Case Reports in Pediatrics
title Mixed Botryoid and Spindle Cell Bladder Rhabdomyosarcoma: An Outstanding Pediatric Case
title_full Mixed Botryoid and Spindle Cell Bladder Rhabdomyosarcoma: An Outstanding Pediatric Case
title_fullStr Mixed Botryoid and Spindle Cell Bladder Rhabdomyosarcoma: An Outstanding Pediatric Case
title_full_unstemmed Mixed Botryoid and Spindle Cell Bladder Rhabdomyosarcoma: An Outstanding Pediatric Case
title_short Mixed Botryoid and Spindle Cell Bladder Rhabdomyosarcoma: An Outstanding Pediatric Case
title_sort mixed botryoid and spindle cell bladder rhabdomyosarcoma an outstanding pediatric case
url http://dx.doi.org/10.1155/2017/8397826
work_keys_str_mv AT tommasoalterio mixedbotryoidandspindlecellbladderrhabdomyosarcomaanoutstandingpediatriccase
AT robertochimenz mixedbotryoidandspindlecellbladderrhabdomyosarcomaanoutstandingpediatriccase
AT salvatorearena mixedbotryoidandspindlecellbladderrhabdomyosarcomaanoutstandingpediatriccase
AT giovanniconti mixedbotryoidandspindlecellbladderrhabdomyosarcomaanoutstandingpediatriccase
AT sabrinacardile mixedbotryoidandspindlecellbladderrhabdomyosarcomaanoutstandingpediatriccase
AT carmeloromeo mixedbotryoidandspindlecellbladderrhabdomyosarcomaanoutstandingpediatriccase
AT carmelosalpietro mixedbotryoidandspindlecellbladderrhabdomyosarcomaanoutstandingpediatriccase
AT carmelofede mixedbotryoidandspindlecellbladderrhabdomyosarcomaanoutstandingpediatriccase