CD55 upregulation in T cells of COVID-19 patients suppresses type-I interferon responses

CD55 upregulation in T cells of COVID-19 patients suppresses type-I interferon responses

Abstract Complement overactivation, has been verified in COVID-19 patients. Complement regulatory proteins, including CD55, control complement overactivation thus eliminating complement deposition and cell lysis. We investigated complement regulatory protein expression in COVID-19 for potential dere...

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Main Authors: Maria G. Detsika, Maria Sakkou, Vassiliki Triantafyllidou, Dimitris Konstantopoulos, Eirini Grigoriou, Katherina Psarra, Edison Jahaj, Ioanna Dimopoulou, Stylianos E. Orfanos, Alexandra Tsirogianni, George Kollias, Anastasia Kotanidou
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08066-z
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