The Takeda Three Colors Combination Test: A Screening Test for Detection of Very Mild Alzheimer’s Disease

Background. Alzheimer’s disease (AD) is the most common type of dementia and is prevalent worldwide. It is expected that AD, for which aging is a risk factor, will increase in the future. Because early detection of AD has become increasingly important, promoting demand for screening tests with adequ...

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Main Authors: Shinya Takeda, Kayo Tajime, Toshiatsu Taniguchi
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/907316
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author Shinya Takeda
Kayo Tajime
Toshiatsu Taniguchi
author_facet Shinya Takeda
Kayo Tajime
Toshiatsu Taniguchi
author_sort Shinya Takeda
collection DOAJ
description Background. Alzheimer’s disease (AD) is the most common type of dementia and is prevalent worldwide. It is expected that AD, for which aging is a risk factor, will increase in the future. Because early detection of AD has become increasingly important, promoting demand for screening tests with adequate sensitivity. In this study, we examined the usefulness of the Takeda Three Colors Combination Test (TTCC) for screening of the very mild AD and amnestic mild cognitive impairment (aMCI). Methods. 154 senior persons participated in the research: 55 with very mild AD, 45 with aMCI, and 54 control group. The TTCC, which was a colored cards configuration memory task, was examined for sensitivity and specificity. Results. The sensitivity of the TTCC was 76% and 47% for the very mild AD and aMCI groups, and the specificity was 83%. Conducting TTCC (including instruction and evaluation) was accomplished within 2 minutes for all subjects. Conclusion. The TTCC is useful screening test for early detection of AD. Furthermore, administration time is short and requires no special training or skills. Thus, we believe the TTCC shows great potential for use as an AD screening test by a general practitioner in communities worldwide.
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spelling doaj-art-dbefa2ec3edb4799a598d48c2e0cb42a2025-02-03T06:01:37ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/907316907316The Takeda Three Colors Combination Test: A Screening Test for Detection of Very Mild Alzheimer’s DiseaseShinya Takeda0Kayo Tajime1Toshiatsu Taniguchi2Department of Clinical Psychology, Tottori University Graduate School of Medical Sciences, 86 Nishicho, Yonago, Tottori Prefecture 683-8503, JapanDepartment of Psychiatry, Tottori Seikyo Hospital, 458 Suehiro-onsen, Tottori, Tottori Prefecture 680-0833, JapanDepartment of Psychiatry, Tottori Seikyo Hospital, 458 Suehiro-onsen, Tottori, Tottori Prefecture 680-0833, JapanBackground. Alzheimer’s disease (AD) is the most common type of dementia and is prevalent worldwide. It is expected that AD, for which aging is a risk factor, will increase in the future. Because early detection of AD has become increasingly important, promoting demand for screening tests with adequate sensitivity. In this study, we examined the usefulness of the Takeda Three Colors Combination Test (TTCC) for screening of the very mild AD and amnestic mild cognitive impairment (aMCI). Methods. 154 senior persons participated in the research: 55 with very mild AD, 45 with aMCI, and 54 control group. The TTCC, which was a colored cards configuration memory task, was examined for sensitivity and specificity. Results. The sensitivity of the TTCC was 76% and 47% for the very mild AD and aMCI groups, and the specificity was 83%. Conducting TTCC (including instruction and evaluation) was accomplished within 2 minutes for all subjects. Conclusion. The TTCC is useful screening test for early detection of AD. Furthermore, administration time is short and requires no special training or skills. Thus, we believe the TTCC shows great potential for use as an AD screening test by a general practitioner in communities worldwide.http://dx.doi.org/10.1155/2014/907316
spellingShingle Shinya Takeda
Kayo Tajime
Toshiatsu Taniguchi
The Takeda Three Colors Combination Test: A Screening Test for Detection of Very Mild Alzheimer’s Disease
The Scientific World Journal
title The Takeda Three Colors Combination Test: A Screening Test for Detection of Very Mild Alzheimer’s Disease
title_full The Takeda Three Colors Combination Test: A Screening Test for Detection of Very Mild Alzheimer’s Disease
title_fullStr The Takeda Three Colors Combination Test: A Screening Test for Detection of Very Mild Alzheimer’s Disease
title_full_unstemmed The Takeda Three Colors Combination Test: A Screening Test for Detection of Very Mild Alzheimer’s Disease
title_short The Takeda Three Colors Combination Test: A Screening Test for Detection of Very Mild Alzheimer’s Disease
title_sort takeda three colors combination test a screening test for detection of very mild alzheimer s disease
url http://dx.doi.org/10.1155/2014/907316
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